Home

FHOD3 (human)

Overview FHOD3 Actin-organizing protein that may cause stress fiber formation together with cell elongation. Belongs to the formin homology family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB. Cellular Component: cytoskeleton; cytoplasm; nucleolus; nucleus Molecular Function: actin binding Biological Process: negative regulation of actin filament polymerization; sarcomere organization Reference #:  Q2V2M9 (UniProtKB) Alt. Names/Synonyms: FH1/FH2 domain-containing protein 3; FHOD3; FHOS2; Formactin-2; Formactin2; Formin homolog overexpressed in spleen 2; formin homology 2 domain containing 3; hFHOS2; KIAA1695 Gene Symbols: FHOD3 Molecular weight: 158,613 Da Basal Isoelectric point: 5.7  Predict pI for various phosphorylation states

Select Structure to View Below FHOD3

STRING  |  Scansite  |  Phospho.ELM  |  Pfam  |  DISEASE  |  Source  |  InnateDB  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		T259	EEKDGVDTELLVYAM
0	1		T267	ELLVYAMTLVNKTLS
0	3		S345-p	CRDRRRAsVCSsGGG
0	1		S349-p	RRAsVCSsGGGEHRG
0	1		S375	QSIKSTLSAPTSPCS
0	1		S379	STLSAPTSPCSQSAP
0	2		-	gap
0	2		-	gap
0	1		S411-p	GNNSYHSsRPSSGSS
0	1		T422-p	SGSSVPTtPTSsVSP
0	1		S426-p	VPTtPTSsVSPPQEA
0	2		S441-p	RLERSSPsGLLtSSF
0	1		T445-p	SSPsGLLtSSFRQHQ
0	1		S763	DLGRGSISPDAEPND
0	1		T775	PNDKVPETAPVQPKT
0	1		T893-p	TFTKKKKtIRLFWNE
0	2		K1117-a	LEKVPEVkDTVHKQS
0	1		S1196-p	PVLKQRMsEFLKDCA
0	1		T1276-p	NHRERNKtRGkMITD
0	1		K1279-a	ERNKtRGkMITDSGk
0	1		K1286-a	kMITDSGkFSGsSPA
0	1		S1290-p	DSGkFSGsSPAPPsQ
0	1		S1296-p	GsSPAPPsQPQGLsY
0	1		S1302-p	PsQPQGLsYAEDAAE
0	1		K1318-a	ENMKAVLkTSSPSVE
0	1		S1389-p	VPRERKRsRANRKSL

	mouse
T259-p	EEKDGVDtELLVYAM
T267-p	ELLVYAMtLVNKTLA
S345-p	HRDRRRAsMCSGGTV
G349	RRAsMCSGGTVGEQQ
S376-p	QNIKSPLsAPTsPCS
S380-p	SPLsAPTsPCSPSVP
T413-p	EEEEQPItEPNsEEE
S417-p	QPItEPNsEEEREDD
S563	SSNSFQSSRPSPGPS
S574	PGPSGSPSYASSFSS
S578	GSPSYASSFSSPQDT
S590-p	QDTRSSPsGLLTSSF
T594	SSPsGLLTSSFRQHQ
S921-p	EVGRGAIsPDVESQD
T933-p	SQDKVPDtPPAQLKT
T1049	AFTKKKKTIRLFWNE
K1273-a	LEKVPEVkDTVHKQS
S1352	PVLKQRMSEFLKDCA
T1432	NHRERNKTRGKMITD
K1435	ERNKTRGKMITDSGK
K1442	KMITDSGKFSGSSPA
S1446	DSGKFSGSSPAAPSQ
S1452	GSSPAAPSQPQGLSY
S1458	PSQPQGLSYAEDAAE
K1474	ENMKAVLKTSSPALE
S1545-p	VPRERKRsRANRKSL

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E Produced by 3rd Millennium  |  Design by Digizyme ©2003-2013 Cell Signaling Technology, Inc.