Home

Bap31 (mouse)

Overview Bap31 May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis. Homodimer and heterodimer with BCAP29. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II. Interacts with PTPLB. Ubiquitous. Belongs to the BCAP29/BCAP31 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB. Protein type: Membrane protein, integral Cellular Component: Golgi membrane; membrane; integral to plasma membrane; endoplasmic reticulum; plasma membrane; integral to membrane; lipid particle Biological Process: vesicle-mediated transport; intracellular protein transport; elevation of cytosolic calcium ion concentration; protein transport; transport; apoptosis; reduction of endoplasmic reticulum calcium ion concentration; positive regulation of caspase activity; immune response; elevation of mitochondrial calcium ion concentration Reference #:  Q61335 (UniProtKB) Alt. Names/Synonyms: accessory protein BAP31; B-cell receptor-associated protein 31; Bap31; Bcap31; BCR-associated protein 31; OTTMUSP00000019276; p28 Gene Symbols: Bcap31 Molecular weight: 27,957 Da Basal Isoelectric point: 8.73  Predict pI for various phosphorylation states Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below Bap31

STRING  |  Scansite  |  Phospho.ELM  |  Pfam  |  Source  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			mouse
0	2		-	gap
0	1		S2	______MSLQWTTVA
0	1		T6	__MSLQWTTVATFLY
0	1		K34	ISPKRWQKVFKSRLV
0	2		K72	DAVREILKYDDVTEK
0	2		K79	KYDDVTEKVNLQNNP
0	4		K95	AMEHFHMKLFRAQRN
0	3		K137	LASNEAFKKQAESAS
0	2		K137	LASNEAFKKQAESAS
0	12		K138	ASNEAFKKQAESASE
0	5		K148	ESASEAAKKYMEEND
0	4		K149	SASEAAKKYMEENDQ
0	13		K158	MEENDQLKKGAAEDG
0	11		K159	EENDQLKKGAAEDGD
0	1		D164	LKKGAAEDGDkLDIG
0	40		K167-u	GAAEDGDkLDIGNTE
0	51		K176-u	DIGNTEMkLEENkSL
0	1		K181-u	EMkLEENkSLKNDLR
0	10		K184	LEENkSLKNDLRKLk
0	1		K189	SLKNDLRKLkDELAS
0	22		K191-u	KNDLRKLkDELASTk
0	1		K191-a	KNDLRKLkDELASTk
0	4		K198-a	kDELASTkKKLEkAE
0	2		K198	kDELASTKKKLEkAE
0	3		K200	ELASTkKKLEkAENE
0	9		K203-u	STkKKLEkAENEALA
0	1		K203	STkKKLEKAENEALA
0	3		K213-u	NEALAMQkQSEGLTk
0	6		K220-u	kQSEGLTkEYDRLLE
0	2		Y222	SEGLTkEYDRLLEEH
0	1		K231-u	RLLEEHAkLQASVRG
0	9		K242	SVRGPSVKKEE____
0	9		K243	VRGPSVKKEE_____

	human ► Hide Isoforms
-	gap
S2	______MSLQWTAVA
T6	__MSLQWTAVATFLY
K34	ISPKRWQKIFKSRLV
K72	DAVREIRKYDDVTEK
K79	KYDDVTEKVNLQNNP
K95	AMEHFHMKLFRAQRN
K137	LASNEAFKKQAESAS
K137	LASNEAFKKQAESAS
K138	ASNEAFKKQAESASE
K148	ESASEAAKKYMEEND
K149	SASEAAKKYMEENDQ
K158	MEENDQLKKGAAVDG
K159	EENDQLKKGAAVDGG
D164	LKKGAAVDGGKLDVG
K167	GAAVDGGKLDVGNAE
K176	DVGNAEVKLEEENRS
R182	VKLEEENRSLKADLQ
K185	EEENRSLKADLQKLK
K190	SLKADLQKLKDELAS
K192	KADLQKLKDELASTK
K192	KADLQKLKDELASTK
K199	KDELASTKQKLEKAE
K199	KDELASTKQKLEKAE
K201	ELASTKQKLEKAENQ
K204	STKQKLEKAENQVLA
K204	STKQKLEKAENQVLA
K214	NQVLAMRKQSEGLTK
K221	KQSEGLTKEYDRLLE
Y223	SEGLTKEYDRLLEEH
K232	RLLEEHAKLQAAVDG
K243	AVDGPMDKKEE____
K244	VDGPMDKKEE_____

	Bap31 iso2
K62-u	KLTSSCGkPSSNRMS
S69	kPSSNRMSLQWTAVA
T73	NRMSLQWTAVATFLY
K101-u	ISPKRWQkIFKSRLV
K139-u	DAVREIRkYDDVTEk
K146-u	kYDDVTEkVNLQNNP
K162-u	AMEHFHMkLFRAQRN
K204-a	LASNEAFkkQAESAS
K204-u	LASNEAFkkQAESAS
K205-u	ASNEAFkkQAESASE
K215-u	ESASEAAkkYMEEND
K216-u	SASEAAkkYMEENDQ
K225-u	MEENDQLkkGAAVdG
K226-u	EENDQLkkGAAVdGG
D231-ca	LkkGAAVdGGkLDVG
K234-u	GAAVdGGkLDVGNAE
K243-u	DVGNAEVkLEEENRS
R249	VkLEEENRSLkADLQ
K252-u	EEENRSLkADLQkLk
K257-u	SLkADLQkLkDELAS
K259-u	kADLQkLkDELASTk
K259	kADLQkLKDELASTk
K266-a	kDELASTkQkLEkAE
K266-u	kDELASTkQkLEkAE
K268-u	ELASTkQkLEkAENQ
K271-u	STkQkLEkAENQVLA
K271-a	STkQkLEkAENQVLA
K281	NQVLAMRKQSEGLTk
K288-u	KQSEGLTkEyDRLLE
Y290-p	SEGLTkEyDRLLEEH
K299	RLLEEHAKLQAAVDG
K310-u	AVDGPMDkkEE____
K311-u	VDGPMDkkEE_____

	rat
-	gap
S2-p	______MsLQWtAVA
T6-p	__MsLQWtAVATFLY
K34	ISPKRWQKIFKSRLV
K72	DAVREIRKYDDVTEK
K79	KYDDVTEKVNLQNNP
K95	AMEHFHMKLFRAQRN
K137	LASNEAFKKQAESAS
K137	LASNEAFKKQAESAS
K138	ASNEAFKKQAESASE
K148	ESASEAAKKYMEEND
K149	SASEAAKKYMEENDQ
K158	MEENDQLKKGTAEDG
K159	EENDQLKKGTAEDGG
D164	LKKGTAEDGGKLDVG
K167	GTAEDGGKLDVGSPE
K176	DVGSPEMKLEENKIL
K181	EMKLEENKILKTDLK
K184	LEENKILKTDLKKLK
K189	ILKTDLKKLKDELAS
K191	KTDLKKLKDELASTK
K191	KTDLKKLKDELASTK
K198	KDELASTKKKLEKAE
K198	KDELASTKKKLEKAE
K200	ELASTKKKLEKAENE
K203	STKKKLEKAENEALA
K203	STKKKLEKAENEALA
K213	NEALAMQKQSEGLTK
K220	KQSEGLTKEYDRLLE
Y222	SEGLTKEYDRLLEEH
K231	RLLEEHAKLQASVRG
K242	SVRGPSDKKEE____
K243	VRGPSDKKEE_____

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E Produced by 3rd Millennium  |  Design by Digizyme ©2003-2013 Cell Signaling Technology, Inc.