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Protein Page:
Bap31 (mouse)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
Bap31 May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis. Homodimer and heterodimer with BCAP29. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II. Interacts with PTPLB. Ubiquitous. Belongs to the BCAP29/BCAP31 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: Golgi membrane; endoplasmic reticulum membrane; mitochondrion; membrane; clathrin-coated vesicle; endoplasmic reticulum; integral to plasma membrane; plasma membrane; integral to membrane; lipid particle
Molecular Function: protein binding; MHC class I protein binding; protein complex binding
Biological Process: vesicle-mediated transport; intracellular protein transport; ER to Golgi vesicle-mediated transport; protein transport; elevation of cytosolic calcium ion concentration; transport; apoptosis; reduction of endoplasmic reticulum calcium ion concentration; positive regulation of caspase activity; immune response; elevation of mitochondrial calcium ion concentration
Reference #:  Q61335 (UniProtKB)
Alt. Names/Synonyms: accessory protein BAP31; B-cell receptor-associated protein 31; Bap31; Bcap31; BCR-associated protein 31; OTTMUSP00000019276; p28
Gene Symbols: Bcap31
Molecular weight: 27,957 Da
Basal Isoelectric point: 8.73  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

Bap31

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       mouse

 
0 2 - gap
0 1 S2 ______MSLQWTTVA
0 1 T6 __MSLQWTTVATFLY
0 1 K34 ISPKRWQKVFKSRLV
0 2 K72 DAVREILKYDDVTEK
0 1 Y73 AVREILKYDDVTEKV
0 2 K79 KYDDVTEKVNLQNNP
0 4 K95 AMEHFHMKLFRAQRN
0 3 K137 LASNEAFKKQAESAS
0 2 K137 LASNEAFKKQAESAS
0 12 K138 ASNEAFKKQAESASE
0 5 K148 ESASEAAKKYMEEND
0 4 K149 SASEAAKKYMEENDQ
0 13 K158 MEENDQLKKGAAEDG
0 11 K159 EENDQLKKGAAEDGD
0 1 D164 LKKGAAEDGDkLDIG
0 40 K167-ub GAAEDGDkLDIGNTE
0 1 K176 DIGNTEMKLEENkSL
0 51 K176-ub DIGNTEMkLEENkSL
0 1 K181-ub EMkLEENkSLKNDLR
0 10 K184 LEENkSLKNDLRKLk
0 1 K189 SLKNDLRKLkDELAS
0 22 K191-ub KNDLRKLkDELASTk
0 2 K191-ac KNDLRKLkDELASTk
0 4 K198-ac kDELASTkKKLEkAE
0 2 K198 kDELASTKKKLEkAE
0 3 K200 ELASTkKKLEkAENE
0 9 K203-ub STkKKLEkAENEALA
0 2 K203 STkKKLEKAENEALA
0 3 K213-ub NEALAMQkQSEGLTk
0 6 K220-ub kQSEGLTkEYDRLLE
0 1 K220-sc kQSEGLTkEYDRLLE
0 2 Y222 SEGLTkEYDRLLEEH
0 1 K231-ub RLLEEHAkLQASVRG
0 9 K242 SVRGPSVKKEE____
0 9 K243 VRGPSVKKEE_____
  human

► Hide Isoforms
 
- gap
S2 ______MSLQWTAVA
T6 __MSLQWTAVATFLY
K34 ISPKRWQKIFKSRLV
K72 DAVREIRKyDDVTEK
Y73-p AVREIRKyDDVTEKV
K79 KyDDVTEKVNLQNNP
K95 AMEHFHMKLFRAQRN
K137 LASNEAFKKQAESAS
K137 LASNEAFKKQAESAS
K138 ASNEAFKKQAESASE
K148 ESASEAAKKYMEEND
K149 SASEAAKKYMEENDQ
K158 MEENDQLKKGAAVDG
K159 EENDQLKKGAAVDGG
D164 LKKGAAVDGGKLDVG
K167 GAAVDGGKLDVGNAE
K176-ac DVGNAEVkLEEENRS
K176 DVGNAEVKLEEENRS
R182 VkLEEENRSLKADLQ
K185 EEENRSLKADLQKLK
K190 SLKADLQKLKDELAS
K192 KADLQKLKDELASTK
K192 KADLQKLKDELASTK
K199 KDELASTKQKLEkAE
K199 KDELASTKQKLEkAE
K201 ELASTKQKLEkAENQ
K204 STKQKLEKAENQVLA
K204-ac STKQKLEkAENQVLA
K214 NQVLAMRKQSEGLTK
K221 KQSEGLTKEYDRLLE
K221 KQSEGLTKEYDRLLE
Y223 SEGLTKEYDRLLEEH
K232 RLLEEHAKLQAAVDG
K243 AVDGPMDKKEE____
K244 VDGPMDKKEE_____
  Bap31 iso2  
K62-ub KLTSSCGkPSSNRMS
S69 kPSSNRMSLQWTAVA
T73 NRMSLQWTAVATFLY
K101-ub ISPKRWQkIFKSRLV
K139-ub DAVREIRkYDDVTEk
Y140 AVREIRkYDDVTEkV
K146-ub kYDDVTEkVNLQNNP
K162-ub AMEHFHMkLFRAQRN
K204-ac LASNEAFkkQAESAS
K204-ub LASNEAFkkQAESAS
K205-ub ASNEAFkkQAESASE
K215-ub ESASEAAkkYMEEND
K216-ub SASEAAkkYMEENDQ
K225-ub MEENDQLkkGAAVdG
K226-ub EENDQLkkGAAVdGG
D231-ca LkkGAAVdGGkLDVG
K234-ub GAAVdGGkLDVGNAE
K243 DVGNAEVKLEEENRS
K243-ub DVGNAEVkLEEENRS
R249 VkLEEENRSLkADLQ
K252-ub EEENRSLkADLQkLk
K257-ub SLkADLQkLkDELAS
K259-ub kADLQkLkDELASTk
K259 kADLQkLKDELASTk
K266-ac kDELASTkQkLEkAE
K266-ub kDELASTkQkLEkAE
K268-ub ELASTkQkLEkAENQ
K271-ub STkQkLEkAENQVLA
K271-ac STkQkLEkAENQVLA
K281 NQVLAMRKQSEGLTk
K288-ub KQSEGLTkEyDRLLE
K288 KQSEGLTKEyDRLLE
Y290-p SEGLTkEyDRLLEEH
K299 RLLEEHAKLQAAVDG
K310-ub AVDGPMDkkEE____
K311-ub VDGPMDkkEE_____
  rat

 
- gap
S2-p ______MsLQWtAVA
T6-p __MsLQWtAVATFLY
K34 ISPKRWQKIFKSRLV
K72 DAVREIRKYDDVTEK
Y73 AVREIRKYDDVTEKV
K79 KYDDVTEKVNLQNNP
K95 AMEHFHMKLFRAQRN
K137 LASNEAFKKQAESAS
K137 LASNEAFKKQAESAS
K138 ASNEAFKKQAESASE
K148 ESASEAAKKYMEEND
K149 SASEAAKKYMEENDQ
K158 MEENDQLKKGTAEDG
K159 EENDQLKKGTAEDGG
D164 LKKGTAEDGGKLDVG
K167 GTAEDGGKLDVGSPE
K176 DVGSPEMKLEENKIL
K176 DVGSPEMKLEENKIL
K181 EMKLEENKILKTDLK
K184 LEENKILKTDLKKLK
K189 ILKTDLKKLKDELAS
K191 KTDLKKLKDELASTK
K191 KTDLKKLKDELASTK
K198 KDELASTKKKLEKAE
K198 KDELASTKKKLEKAE
K200 ELASTKKKLEKAENE
K203 STKKKLEKAENEALA
K203 STKKKLEKAENEALA
K213 NEALAMQKQSEGLTK
K220 KQSEGLTKEYDRLLE
K220 KQSEGLTKEYDRLLE
Y222 SEGLTKEYDRLLEEH
K231 RLLEEHAKLQASVRG
K242 SVRGPSDKKEE____
K243 VRGPSDKKEE_____
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