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Protein Page:
ASPSCR1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
ASPSCR1 Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface. Interacts with GLUT4. Ubiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Vesicle protein; Membrane protein, peripheral
Cellular Component: internal side of plasma membrane; extrinsic to membrane; perinuclear region of cytoplasm; endomembrane system; vesicle membrane; cytosol; nucleus
Molecular Function: protein binding
Biological Process: intracellular protein transport; regulation of glucose import; glucose homeostasis
Reference #:  Q9BZE9 (UniProtKB)
Alt. Names/Synonyms: Alveolar soft part sarcoma chromosomal region candidate gene 1 protein; alveolar soft part sarcoma chromosome region, candidate 1; Alveolar soft part sarcoma locus; ASPC1; ASPCR1; ASPL; ASPS; ASPSCR1; FLJ45380; RCC17; renal cell carcinoma gene on chromosome 17; renal cell carcinoma, papillary, 17; Renal papillary cell carcinoma protein 17; Tether containing UBX domain for GLUT4; TUG; UBX domain protein 9; UBX domain-containing protein 9; UBXD9; UBXN9
Gene Symbols: ASPSCR1
Molecular weight: 60,183 Da
Basal Isoelectric point: 6.23  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ASPSCR1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 1 T23 APNGRRHTVKVTPST
0 1 K75-ub ANLPNNAkLEMVPAS
0 1 T167 GLTGGSATIRFVMKC
0 1 - gap
0 8 S184 PVGKTPGSLGSSASA
0 2 S187 KTPGSLGSSASAGQA
0 1 S188 TPGSLGSSASAGQAA
0 3 S190 GSLGSSASAGQAAAS
0 1 A198 AGQAAASAPLPLESG
0 1 P258 RLGGPPGPTRPLtss
0 2 T263-p PGPTRPLtsssAKLP
0 7 S264-p GPTRPLtsssAKLPK
0 1 S265-p PTRPLtsssAKLPKS
0 2 S266-p TRPLtsssAKLPKSL
0 1 P270 tsssAKLPKSLssPG
0 1 S274-p AKLPKSLssPGGPSk
0 2 S275-p KLPKSLssPGGPSkP
0 1 K281-ac ssPGGPSkPKKSKSG
0 1 K374 EEAPLVTKAFREAQI
0 1 - gap
0 1 - gap
0 2 A498 ARYMSRAAGsPsPLP
0 10 S500-p YMSRAAGsPsPLPAP
0 6 S502-p SRAAGsPsPLPAPDP
0 1 P511 LPAPDPAPKSEPAAE
0 1 S513 APDPAPKSEPAAEEG
0 9 K552-ac WLKLPASkR______
  ASPSCR1 iso2  
T23 APNGRRHTVKVTPST
K75 ANLPNNAKLEMVPAS
T167 GLTGGSATIRFVMKC
- gap
S184 PVGKTPGSLGSSASA
S187 KTPGSLGSSASAGQA
S188 TPGSLGSSASAGQAA
S190 GSLGSSASAGQAAAS
A198 AGQAAASAPLPLESG
P258 RLGGPPGPTRPLTSS
T263 PGPTRPLTSSSAKLP
S264 GPTRPLTSSSAKLPK
S265 PTRPLTSSSAKLPKS
S266 TRPLTSSSAKLPKSL
P270 TSSSAKLPKSLSSPG
S274 AKLPKSLSSPGGPSK
S275 KLPKSLSSPGGPSKP
K281 SSPGGPSKPKKSKSG
K374 EEAPLVTKAFREAQI
- gap
S499-p RLLFWGPsRGRASPS
A592 ARYMSRAAGSPSPLP
S594 YMSRAAGSPSPLPAP
S596 SRAAGSPSPLPAPDP
P605 LPAPDPAPKSEPAAE
S607 APDPAPKSEPAAEEG
K646 WLKLPASKR______
  ASPSCR1 iso4  
- gap
- gap
T90 GLTGGSATIRFVMKC
- gap
S107 PVGKTPGSLGSSASA
S110 KTPGSLGSSASAGQA
S111 TPGSLGSSASAGQAA
S113 GSLGSSASAGQAAAS
A121 AGQAAASAPLPLESG
P181 RLGGPPGPTRPLTSS
T186 PGPTRPLTSSSAKLP
S187 GPTRPLTSSSAKLPK
S188 PTRPLTSSSAKLPKS
S189 TRPLTSSSAKLPKSL
P193 TSSSAKLPKSLSSPG
S197 AKLPKSLSSPGGPSK
S198 KLPKSLSSPGGPSKP
K204 SSPGGPSKPKKSKSG
K297 EEAPLVTKAFREAQI
S317-p RYPRRSLsLSPRLES
- gap
- gap
- gap
- gap
- gap
- gap
- gap
  mouse

 
T23 APNGRRHTVKVTPST
K75 ANLPNNAKLEMVPVS
T167-p GLTGGSAtIRFVIKQ
S188-p QESIAVRsKAPGsPV
S193-p VRsKAPGsPVssLsA
S196-p KAPGsPVssLsADQA
S197-p APGsPVssLsADQAS
S199-p GsPVssLsADQASSS
T207-p ADQASSStLLPLNSG
S273-p RLGGPSAsLRPLtsP
T278-p SAsLRPLtsPsANSs
S279-p AsLRPLtsPsANSsK
P280 sLRPLtsPsANSsKS
S281-p LRPLtsPsANSsKSF
S285-p tsPsANSsKSFSGPG
S289 ANSsKSFSGPGGPSK
G290 NSsKSFSGPGGPSKP
K296 SGPGGPSKPKKPKPG
K370-ub EEAPLVTkAFREAQM
- gap
- gap
S494-p ARCMSRAsGsPPLLP
S496-p CMSRAsGsPPLLPAP
P498 SRAsGsPPLLPAPDP
S507-p LPAPDPVsLEsEPIA
S510-p PDPVsLEsEPIAEDG
K549 WLKLPASKR______
  rat

 
T23-p APNGRRHtVKVTPST
K75 ANLPNNAKLEMVPAS
T167 GLTGGSATIRFVIKQ
S188 QESIAVRSKPPGsPV
S193-p VRSKPPGsPVSSMSA
S196 KPPGsPVSSMSADQA
S197 PPGsPVSSMSADQAS
S199 GsPVSSMSADQASSS
P207 ADQASSSPLLPLNSG
S274 RLGGPSVSLRSLTSP
T279 SVSLRSLTSPAAKSS
S280 VSLRSLTSPAAKSST
P281 SLRSLTSPAAKSSTS
A282 LRSLTSPAAKSSTSF
S286 TSPAAKSSTSFSGPG
S290 AKSSTSFSGPGGPSK
G291 KSSTSFSGPGGPSKP
K297 SGPGGPSKPKKSKPG
K371 EEAPLVTKAFREAQM
- gap
- gap
A474 ARCMSRAAGSPSLLP
S476 CMSRAAGSPSLLPAP
S478 SRAAGSPSLLPAPDP
S487 LPAPDPVSLDSEPIA
S490 PDPVSLDSEPIAEEG
K529 WLKLPASKR______
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