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Protein Page:
PVA (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
PVA In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Belongs to the parvalbumin family. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: protein complex; axon; cytoplasm; nucleus
Molecular Function: protein homodimerization activity; protein heterodimerization activity; calcium ion binding
Biological Process: cytosolic calcium ion homeostasis
Reference #:  P20472 (UniProtKB)
Alt. Names/Synonyms: D22S749; MGC116759; parvalbumin; Parvalbumin alpha; PRVA; PVALB
Gene Symbols: PVALB
Molecular weight: 12,059 Da
Basal Isoelectric point: 4.98  Predict pI for various phosphorylation states
Select Structure to View Below

PVA

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 N8 MSMTDLLNAEDIKKA
0 1 K14 LNAEDIKKAVGAFSA
0 2 K28 ATDSFDHKKFFQMVG
0 2 K28 ATDSFDHKKFFQMVG
0 1 K29 TDSFDHKKFFQMVGL
0 1 K29 TDSFDHKKFFQMVGL
0 1 K37 FFQMVGLKKKSADDV
0 2 K37 FFQMVGLKKKSADDV
0 1 K39 QMVGLKKKSADDVKK
0 1 K46 KSADDVKKVFHMLDK
0 1 K53 KVFHMLDKDKSGFIE
0 1 K53 KVFHMLDKDKSGFIE
0 1 K55 FHMLDKDKSGFIEED
0 1 K55 FHMLDKDKSGFIEED
0 1 K69 DELGFILKGFSPDAR
0 2 K69 DELGFILKGFSPDAR
0 2 P73 FILKGFSPDARDLSA
0 1 S79 SPDARDLSAKEtkML
0 1 K81 DARDLSAKEtkMLMA
0 2 T83-p RDLSAKEtkMLMAAG
0 1 K84-ac DLSAKEtkMLMAAGD
0 2 K84 DLSAKEtKMLMAAGD
0 1 K92 MLMAAGDKDGDGkIG
0 1 K97-ac GDKDGDGkIGVDEFS
0 1 T105 IGVDEFSTLVAES__
  mouse

 
S8-p MSMTDVLsAEDIKkA
K14-ub LsAEDIKkAIGAFAA
K28-ac AADSFDHkkFFQMVG
K28-ub AADSFDHkkFFQMVG
K29-ac ADSFDHkkFFQMVGL
K29-ub ADSFDHkkFFQMVGL
K37-ac FFQMVGLkKkNPDEV
K37-ub FFQMVGLkKkNPDEV
K39-ub QMVGLkKkNPDEVKk
K46-ub kNPDEVKkVFHILDk
K53-ac kVFHILDkDkSGFIE
K53-ub kVFHILDkDkSGFIE
K55-ac FHILDkDkSGFIEED
K55-ub FHILDkDkSGFIEED
K69-ac DELGSILkGFSsDAR
K69-ub DELGSILkGFSsDAR
S73-p SILkGFSsDARDLsA
S79-p SsDARDLsAkEtkTL
K81-ub DARDLsAkEtkTLLA
T83-p RDLsAkEtkTLLAAG
K84 DLsAkEtKTLLAAGD
K84-ub DLsAkEtkTLLAAGD
K92-ub TLLAAGDkDGDGKIG
K97 GDkDGDGKIGVEEFS
T105-p IGVEEFStLVAES__
  rat

 
S8-p MSMTDLLsAEDIKKA
K14 LsAEDIKKAIGAFTA
K28 AADSFDHKkFFQMVG
K28 AADSFDHKkFFQMVG
K29-ac ADSFDHKkFFQMVGL
K29 ADSFDHKKFFQMVGL
K37 FFQMVGLKKKSADDV
K37 FFQMVGLKKKSADDV
K39 QMVGLKKKSADDVKK
K46 KSADDVKKVFHILDK
K53 KVFHILDKDkSGFIE
K53 KVFHILDKDkSGFIE
K55-ac FHILDKDkSGFIEED
K55 FHILDKDKSGFIEED
K69 DELGSILKGFSsDAR
K69 DELGSILKGFSsDAR
S73-p SILKGFSsDARDLSA
S79 SsDARDLSAKETkTL
K81 DARDLSAKETkTLMA
T83 RDLSAKETkTLMAAG
K84-ac DLSAKETkTLMAAGD
K84 DLSAKETKTLMAAGD
K92 TLMAAGDKDGDGKIG
K97 GDKDGDGKIGVEEFS
T105 IGVEEFSTLVAES__
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