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RKIP
a phosphatidylethanolamine-binding protein. Has lower affinity for phosphatidylinositol and phosphatidylcholine. May be involved in the function of the presynaptic cholinergic neurons of the central nervous system. Increases the production of choline acetyltransferase but not acetylcholinesterase. Expressed in brain. Increased expression in aged senescence-accelerated mice. Note: This description may include information from UniProtKB.
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| Protein type: Inhibitor protein |
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Cellular Component: Golgi apparatus; extracellular space; synaptic vesicle; mitochondrial outer membrane; cell surface; rough endoplasmic reticulum; cell soma; apical part of cell; nerve terminal
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Molecular Function: serine-type endopeptidase inhibitor activity; phosphatidylethanolamine binding; mitogen-activated protein kinase binding; ATP binding; receptor binding
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Biological Process: response to drug; response to cAMP; positive regulation of mitosis; eating behavior; negative regulation of MAPKKK cascade; regulation of neurotransmitter levels; MAPKKK cascade; response to ethanol; negative regulation of protein amino acid phosphorylation; response to heat; response to wounding; response to oxidative stress; brain development; response to activity; response to calcium ion; response to electrical stimulus; spermatid development; regulation of the force of heart contraction; aging; response to corticosterone stimulus
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Reference #:
P30086 (UniProtKB)
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| Alt. Names/Synonyms: HCNP; HCNPpp; Hippocampal cholinergic neurostimulating peptide; Neuropolypeptide h3; PBP; PEBP; PEBP-1; PEBP1; phosphatidylethanolamine binding protein 1; Phosphatidylethanolamine-binding protein 1; prostatic binding protein; Prostatic-binding protein; Raf kinase inhibitor protein; Raf kinase inhibitory protein; RKIP |
| Gene Symbols: PEBP1 |
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Molecular weight: 21,057 Da
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Basal Isoelectric point: 7.01
Predict pI for various phosphorylation states
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Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®
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