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GARNL3 (human)

Overview GARNL3 Belongs to the GARNL3 family. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB. Protein type: GTPase activating protein, misc. Cellular Component: intracellular Molecular Function: GTPase activator activity; small GTPase regulator activity Biological Process: regulation of small GTPase mediated signal transduction Reference #:  Q5VVW2 (UniProtKB) Alt. Names/Synonyms: bA356B19.1; DKFZp434O131; DKFZp761J1523; FLJ38360; GARL3; GARNL3; GTPase activating RANGAP domain-like 3; GTPase activating Rap/RanGAP domain-like 3; GTPase-activating Rap/Ran-GAP domain-like protein 3 Gene Symbols: GARNL3 Molecular weight: 112,852 Da Basal Isoelectric point: 7.57  Predict pI for various phosphorylation states

Select Structure to View Below GARNL3

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	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		-	gap
0	2		S28	HFCSSSVSEDLGCRR
0	2		S45	FSRKHYGSVELLIss
0	1		S51-p	GSVELLIssDADGAI
0	1		S52-p	SVELLIssDADGAIQ
0	1		Y155-p	TQKICLPysPtKTLS
0	1		S156-p	QKICLPysPtKTLSV
0	1		T158-p	ICLPysPtKTLSVKS
0	7		K395-a	ETPTFAQkRRRtLDM
0	1		T399-p	FAQkRRRtLDMLIRS
0	1		S424	KNMLNRRSFSDVLPE
0	4		S426	MLNRRSFSDVLPEsP
0	4		S432-p	FSDVLPEsPKSARKK
0	1		S467	VRGDAPSSLAASGIC
0	1		K617-a	KLLLITRkHNKPSGV
0	1		K817-u	VSSGGSSkGAsARNs
0	2		S820-p	GGSSkGAsARNsPQt
0	2		N823	SkGAsARNsPQtPPG
0	4		S824-p	kGAsARNsPQtPPGR
0	5		T827-p	sARNsPQtPPGRDTP
0	1		T833	QtPPGRDTPVFPSSL
0	2		S869-p	SIERPLKsPLVSKVI
0	1		T877	PLVSKVITPPTPISV
0	1		S994-p	DREGSPVsGsSPFQL
0	1		S996-p	EGSPVsGsSPFQLTA
0	1		S1005-p	PFQLTAFsDEDIIDL

	mouse ► Hide Isoforms
-	gap
S51	SQVNLSVSEDLGCRR
S68-p	FSRKHYGsVELLISS
S74	GsVELLISSDADGAI
S75	sVELLISSDADGAIQ
Y178	TQKICLPYSPTKTLS
S179	QKICLPYSPTKTLSV
T181	ICLPYSPTKTLSVKS
K418-a	ETPTFAQkRRRTLDM
T422	FAQkRRRTLDMLIRS
S447-p	KNMLNRRsFsDVLPE
S449-p	MLNRRsFsDVLPEsP
S455-p	FsDVLPEsPKSARKK
S490-p	VRGDAPSsLAASGMC
K640	KLLLITRKPHNKPSG
K841	GSSGGSSKGAsAHts
S844-p	GGSSKGAsAHtsPQt
T847-p	SKGAsAHtsPQtPPA
S848-p	KGAsAHtsPQtPPAR
T851-p	sAHtsPQtPPARDtP
T857-p	QtPPARDtPLFPSSL
S893-p	SIERPLKsPLVSKVI
T901-p	PLVSKVItPPTSIGL
S1019	DKEGSPGSGSSPFQL
S1021	EGSPGSGSSPFQLMA
S1030	PFQLMASSEEDIIDL

	GARNL3 iso2
-	gap
S6-p	__MKSSVsEDLGCRR
S23	FSRKHYGSVELLISS
S29	GSVELLISSDADGAI
S30	SVELLISSDADGAIQ
Y133	TQKICLPYSPTKTLS
S134	QKICLPYSPTKTLSV
T136	ICLPYSPTKTLSVKS
K373	ETPTFAQKRRRTLDM
T377	FAQKRRRTLDMLIRS
S402	KNMLNRRSFSDVLPE
S404	MLNRRSFSDVLPESP
S410	FSDVLPESPKSARKK
S445	VRGDAPSSLAASGMC
K595	KLLLITRKPHNKPSG
K796	GSSGGSSKGASAHTS
S799	GGSSKGASAHTSPQT
T802	SKGASAHTSPQTPPA
S803	KGASAHTSPQTPPAR
T806	SAHTSPQTPPARDTP
T812	QTPPARDTPLFPSSL
S848	SIERPLKSPLVSKVI
T856	PLVSKVITPPTSIGL
S974	DKEGSPGSGSSPFQL
S976	EGSPGSGSSPFQLMA
S985	PFQLMASSEEDIIDL

	GARNL3 iso3
S26-p	ALRRRGCsFESPSTA
S91	SQVNLSVSEDLGCRR
S108	FSRKHYGSVELLISS
S114	GSVELLISSDADGAI
S115	SVELLISSDADGAIQ
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	under review
-	gap
-	under review
-	gap
-	gap
-	gap

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