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Protein Page:
ANGPT4 (human)

Overview
ANGPT4 Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; Secreted
Cellular Component: extracellular space; extracellular region
Molecular Function: transmembrane receptor protein tyrosine kinase activator activity; receptor tyrosine kinase binding
Biological Process: negative regulation of angiogenesis; positive regulation of angiogenesis; positive regulation of peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activation (dimerization); endothelial cell proliferation; positive regulation of blood vessel endothelial cell migration; angiogenesis; blood coagulation; negative regulation of blood vessel endothelial cell migration; leukocyte migration; negative regulation of apoptosis
Reference #:  Q9Y264 (UniProtKB)
Alt. Names/Synonyms: AGP4; ANG-3; ANG-4; ANG3; ANG4; angiopoietin 4; Angiopoietin-3; Angiopoietin-4; ANGP4; ANGPT4; dJ824F16.2 (angiopoietin 4); MGC138181; MGC138183
Gene Symbols: ANGPT4
Molecular weight: 56,849 Da
Basal Isoelectric point: 9.1  Predict pI for various phosphorylation states
Select Structure to View Below

ANGPT4

Protein Structure Not Found.


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