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ADARB2 (human)

Overview ADARB2 Does not act on glutamate receptor or on serotonin receptor subtype 2C. Capable of binding to dsRNA but also to ssRNA. Note: This description may include information from UniProtKB. Protein type: EC 3.5.-.-; Hydrolase; RNA binding protein Cellular Component: mitochondrion; cytoplasm; nucleolus; nucleus Molecular Function: adenosine deaminase activity; single-stranded RNA binding; metal ion binding; double-stranded RNA binding Biological Process: mRNA processing Reference #:  Q9NS39 (UniProtKB) Alt. Names/Synonyms: ADAR3; ADARB2; adenosine deaminase, RNA-specific, B2; adenosine deaminase, RNA-specific, B2 (RED1 homolog rat); adenosine deaminase, RNA-specific, B2 (RED2 homolog rat); Double-stranded RNA-specific editase B2; dsRNA adenosine deaminase B2; FLJ25034; FLJ36975; homolog of rat BLUE; hRED2; RED2; RNA-dependent adenosine deaminase 3; RNA-editing deaminase 2; RNA-editing enzyme 2 Gene Symbols: ADARB2 Molecular weight: 80,621 Da Basal Isoelectric point: 10.19  Predict pI for various phosphorylation states

Select Structure to View Below ADARB2

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	Modification Sites and Domains

	Modification Sites in Parent Protein, Orthologs, and Isoforms

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		T41-p	DKVSILStFLAPFKH
0	1		T54-p	KHLSPGItNtEDDDT
0	1		T56-p	LSPGItNtEDDDTLS
0	1		T316-p	AVSVDGRtFEGsGRs
0	1		S320-p	DGRtFEGsGRsKKLA
0	1		S323-p	tFEGsGRsKKLARGQ
0	1		S612-p	GVGQLPAsYRHNRPL
0	1		S634-p	EARQPGKsPPFsMNW
0	1		S638-p	PGKsPPFsMNWVVGS
0	1		S688	RLSTRTPSPGDTPSM
0	2		Y696-p	PGDTPSMyCEAKLGA

	mouse
T41	DKVSILSTFLAPFKY
T54	KYLSPGTTNTEDEDN
T56	LSPGTTNTEDEDNLS
T322	AVCVDGRTFEGSGRS
S326	DGRTFEGSGRSKKLA
S329	TFEGSGRSKKLAKGQ
S618	GIGQLPASYRQNRPL
S640	EARQPGKSPHFSANW
S644	PGKSPHFSANWVVGS
S694-p	RLSTRIPsHGDTPSM
Y702-p	HGDTPSMyCEAKQGA

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