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IL17A
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. Belongs to the IL-17 family. Note: This description may include information from UniProtKB.
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| Protein type: Secreted, signal peptide; Secreted |
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Cellular Component: extracellular space; extracellular region; external side of plasma membrane
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Molecular Function: cytokine activity
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Biological Process: positive regulation of interleukin-23 production; positive regulation of osteoclast differentiation; positive regulation of transcription from RNA polymerase II promoter; inflammatory response
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Reference #:
Q62386 (UniProtKB)
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| Alt. Names/Synonyms: CTLA-8; Ctla8; Cytotoxic T-lymphocyte-associated antigen 8; IL-17; IL-17A; Il17; Il17a; interleukin 17A; Interleukin-17A |
| Gene Symbols: Il17a |
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Molecular weight: 17,490 Da
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Basal Isoelectric point: 9.19
Predict pI for various phosphorylation states
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