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Protein Page:
IL17A (human)

Overview
IL17A Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. Belongs to the IL-17 family. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 6p12
Cellular Component: extracellular space; external side of plasma membrane
Molecular Function: cytokine activity
Biological Process: cell death; cell-cell signaling; positive regulation of osteoclast differentiation; apoptosis; positive regulation of interleukin-23 production; protein amino acid glycosylation; immune response; positive regulation of transcription from RNA polymerase II promoter; inflammatory response
Reference #:  Q16552 (UniProtKB)
Alt. Names/Synonyms: CTLA-8; CTLA8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; cytotoxic T-lymphocyte-associated serine esterase 8; IL-17; IL-17A; IL17; IL17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; Interleukin-17A
Gene Symbols: IL17A
Molecular weight: 17,504 Da
Basal Isoelectric point: 8.82  Predict pI for various phosphorylation states
Select Structure to View Below

IL17A

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 2 S36-p RNPGCPNsEDKNFPR
  mouse

 
T38 QSSACPNTEAKDFLQ
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