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IL17A (human)

Overview IL17A Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. Belongs to the IL-17 family. Note: This description may include information from UniProtKB. Protein type: Secreted, signal peptide; Secreted Cellular Component: extracellular space; external side of plasma membrane Molecular Function: cytokine activity Biological Process: cell death; cell-cell signaling; positive regulation of osteoclast differentiation; apoptosis; positive regulation of interleukin-23 production; protein amino acid glycosylation; immune response; positive regulation of transcription from RNA polymerase II promoter; inflammatory response Reference #:  Q16552 (UniProtKB) Alt. Names/Synonyms: CTLA-8; CTLA8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; cytotoxic T-lymphocyte-associated serine esterase 8; IL-17; IL-17A; IL17; IL17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; Interleukin-17A Gene Symbols: IL17A Molecular weight: 17,504 Da Basal Isoelectric point: 8.82  Predict pI for various phosphorylation states

Select Structure to View Below IL17A 2VXS - A/D/C/B=20-155 (human)

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB  |  Phospho3D  |  DISEASE  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains

	Modification Sites in Parent Protein, Orthologs, and Isoforms

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	2		S36-p	RNPGCPNsEDKNFPR

	mouse
-	under review

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