Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, Ser/Thr (non-receptor); EC 18.104.22.168; Protein kinase, Other; Kinase, protein; Other group; NAK family
Chromosomal Location of Human Ortholog: 4p16
Cellular Component: Golgi apparatus; focal adhesion; intracellular membrane-bound organelle; membrane; perinuclear region of cytoplasm
Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding
Biological Process: endoplasmic reticulum organization and biogenesis; epidermal cell differentiation; cell cycle; forebrain morphogenesis; protein amino acid phosphorylation; Golgi organization and biogenesis; cell development
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.