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ATG12 (mouse)

Overview ATG12 Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5. Ubiquitous. Belongs to the ATG12 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB. Protein type: Ubiquitin-like modifier; Autophagy Cellular Component: protein complex; membrane; pre-autophagosomal structure membrane; cytoplasm Molecular Function: protein binding Biological Process: autophagy; autophagic vacuole formation Reference #:  Q9CQY1 (UniProtKB) Alt. Names/Synonyms: 4931423H11Rik; A330058M13Rik; Apg12; APG12-like; Apg12l; Atg12; Atg12l; autophagy 12-like; autophagy-related 12 (yeast); autophagy-related 12-like; Autophagy-related protein 12 Gene Symbols: Atg12 Molecular weight: 15,207 Da Basal Isoelectric point: 4.9  Predict pI for various phosphorylation states CST Pathways:  Autophagy Signaling Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below ATG12 4GDK - F/C=11-43 (human) 4GDL - C=11-43 (human)

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	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			mouse
0	1		K61	KKIDILLKAVGDTPI
0	1		T66	LLKAVGDTPIMKTKK
0	2		K70	VGDTPIMKTKKWAVE
0	1		T71	GDTPIMKTKKWAVER
0	3		K90-u	QGLIDFIkKFLKLVA

	human
K60-u	KKIDILLkAVGDtPI
T65-p	LLkAVGDtPIMktKK
K69-u	VGDtPIMktKKWAVE
T70-p	GDtPIMktKKWAVER
K89-u	QGLIDFIkKFLKLVA

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