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Protein Page:
ATG12 (mouse)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
ATG12 Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5. Ubiquitous. Belongs to the ATG12 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Autophagy; Ubiquitin-like modifier
Cellular Component: protein complex; membrane; cytoplasm; pre-autophagosomal structure membrane
Molecular Function: protein binding
Biological Process: immune system process; innate immune response; autophagy; autophagic vacuole formation
Reference #:  Q9CQY1 (UniProtKB)
Alt. Names/Synonyms: 4931423H11Rik; A330058M13Rik; Apg12; APG12-like; Apg12l; Atg12; Atg12l; autophagy 12-like; autophagy-related 12 (yeast); autophagy-related 12-like; Autophagy-related protein 12
Gene Symbols: Atg12
Molecular weight: 15,207 Da
Basal Isoelectric point: 4.9  Predict pI for various phosphorylation states
CST Pathways:  Autophagy Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ATG12

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       mouse

 
0 1 K61 KKIDILLKAVGDTPI
0 2 K70 VGDTPIMKTKKWAVE
0 3 K90-u QGLIDFIkKFLKLVA
  human

 
K60-u KKIDILLkAVGDTPI
K69-u VGDTPIMkTKKWAVE
K89-u QGLIDFIkKFLKLVA
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