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Protein Page:
PLAGL1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
PLAGL1 Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 6q24-q25
Cellular Component: nucleoplasm; Golgi apparatus; intracellular membrane-bound organelle; nucleus
Molecular Function: DNA binding; metal ion binding
Biological Process: transcription from RNA polymerase II promoter; apoptosis; positive regulation of transcription from RNA polymerase II promoter; cell cycle arrest; cell differentiation
Disease: Diabetes Mellitus, Transient Neonatal, 1
Reference #:  Q9UM63 (UniProtKB)
Alt. Names/Synonyms: DKFZp781P1017; Lost on transformation 1; LOT-1; LOT1; MGC126275; MGC126276; PLAG-like 1; PLAGL1; PLAL1; pleiomorphic adenoma gene-like 1; pleiomorphic adenoma gene-like protein 1; Pleiomorphic adenoma-like protein 1; Tumor supressor ZAC; ZAC; ZAC tumor supressor; ZAC1; Zinc finger protein PLAGL1
Gene Symbols: PLAGL1
Molecular weight: 50,819 Da
Basal Isoelectric point: 8.85  Predict pI for various phosphorylation states
Select Structure to View Below

PLAGL1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 R46 CGKAFVSRYKLMRHM
0 1 S229-p LSTFHTIsPSFQLKA
0 1 Y303-p PPLPNHKyNTTSTSy
0 1 Y310-p yNTTSTSySPLASLP
0 1 K323 LPLKADTKGFCNISL
  mouse

 
K46-ac CGKAFVSkYKLMRHM
A229 QSNFQLIAPSTSFQI
Y408 IILQEHKYNPVPTSY
Y415 YNPVPTSYAPFVGMP
K428-ub MPVKADGkAFCNVGF
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