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PHKG2 (human)

Overview PHKG2 a Ca(2 )/calmodulin-dependent protein kinase of the PHK family. Phosphorylase kinase is a polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin. This isozyme may regulate glycogeneolysis in the testis. Note: This description may include information from UniProtKB. Protein type: Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.19; Protein kinase, CAMK; EC 2.7.11.26; EC 2.7.11.1; Kinase, protein; CAMK group; PHK family Cellular Component: phosphorylase kinase complex; cytosol Molecular Function: calmodulin binding; protein serine/threonine kinase activity; phosphorylase kinase activity; enzyme binding; tau-protein kinase activity; ATP binding Biological Process: glycogen metabolic process; glycogen biosynthetic process; generation of precursor metabolites and energy; glycogen catabolic process; carbohydrate metabolic process; glucose metabolic process; protein amino acid phosphorylation; positive regulation of glycogen catabolic process Reference #:  P15735 (UniProtKB) Alt. Names/Synonyms: GSD9C; PHK-gamma-T; PHKG2; Phosphorylase b kinase gamma catalytic chain, testis/liver isoform; Phosphorylase kinase subunit gamma-2; phosphorylase kinase, gamma 2 (testis); Phosphorylase kinase, gamma 2 (testis/liver); PSK-C3 Gene Symbols: PHKG2 Molecular weight: 46,442 Da Basal Isoelectric point: 5.95  Predict pI for various phosphorylation states

Select Structure to View Below PHKG2 2Y7J - A/D/C/B=6-293 (human)

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	Modification Sites and Domains

	Modification Sites in Parent Protein, Orthologs, and Isoforms

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		Y24-p	AKEFYQKyDPKDVIG
0	1		S35-p	DVIGRGVsSVVRRCV
0	1		T190-p	KLRELCGtPGYLAPE
0	2		T303-p	GSQPWNLtPRQRFRV

	mouse
Y24	AKEFYQKYDPKDIIG
S35	DIIGRGVSSVVRRCV
T190	KLRELCGTPGYLAPE
T303	GSQPWNLTPRQRFRV

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