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Protein Page:
NuaK2 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
NuaK2 a Ca(2+)/calmodulin-dependent protein kinase of the CAMKL family. Note: This description may include information from UniProtKB.
Protein type: Kinase, protein; Protein kinase, CAMK; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); CAMK group; CAMKL family; NuaK subfamily
Molecular Function: protein serine/threonine kinase activity; protein binding; magnesium ion binding; ATP binding
Biological Process: cellular response to glucose starvation; apoptosis; actin cytoskeleton organization and biogenesis; protein amino acid phosphorylation; negative regulation of apoptosis
Reference #:  Q9H093 (UniProtKB)
Alt. Names/Synonyms: DKFZp434J037; DKFZp686F01113; FLJ90349; NUAK family SNF1-like kinase 2; NUAK family, SNF1-like kinase, 2; NUAK2; SNARK; SNF1/AMP activated protein kinase; SNF1/AMP kinase-related kinase
Gene Symbols: NUAK2
Molecular weight: 69,612 Da
Basal Isoelectric point: 9.01  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

NuaK2

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S30-p LAEGLIKsPKPLMKK
0 1 R42 MKKQAVKRHHHKHNL
0 1 T58-p HRYEFLEtLGKGTYG
0 1 Y131-p KIVIVMEyASRGDLy
0 2 Y138-p yASRGDLyDYIsERQ
0 2 S142-p GDLyDYIsERQQLSE
1 0 T208-p HQGKFLQtFCGSPLY
1 1 Y267-p KQISNGAyREPPKPS
0 2 S435-p ELSPIPAsPGQAAPL
0 1 S462-p RESGYYSsPEPSESG
0 1 S523-p AAPTTFGsLDELAPP
0 1 S544-p SRPSGAVsEDsILSS
0 1 S547-p SGAVsEDsILSSEsF
0 1 S553-p DsILSSEsFDQLDLP
0 2 S573 PPLRGCVSVDNLTGL
  mouse

 
S34 LADGLIKSPKPLMKK
R46-m1 MKKQAVKrHHHKHNL
T62 HRYEFLETLGKGTYG
Y143 KIVIVMEYASRGDLy
Y150-p YASRGDLyDYIsERP
S154-p GDLyDYIsERPRLSE
T220 HKGKFLQTFCGSPLY
Y279 KQISNGAYREPPKPS
T447 ELRPVPDTPGQPVPA
S477 RESGYYSSPEPSESG
S538 TTPSTFGSLDQLASS
S559 SRPSGAVSEDSILSS
S562 SGAVSEDSILSSESF
S568 DSILSSESFDQLDLP
S588-p TPLRGCVsVDNLRGL
  rat

 
S34 LADRLIKSPKPLMKK
R46 MKKQAVKRHHHKHNL
T62 HRYEFLETLGKGTYG
Y135 KIVIVMEYASRGDLY
Y142 YASRGDLYDYISERP
S146 GDLYDYISERPRLNE
T212 HKGKFLQTFCGSPLY
Y271 KQISSGAYREPCKPS
T439 ELRPVSNTPGQPVPA
S469 RESGYYSSPEPSESG
S529 TAPSTFGSLDQLASP
S550 SRPSGAVSEDSILSS
S553 SGAVSEDSILSSESF
S559 DSILSSESFDQLDLP
S579 TPLRGCVSVDNLRRL
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