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Protein Page:
MARK2 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
MARK2 a CAMK protein kinase of the CAMKL group. Plays a role in epithelial morphogenesis. Modulates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery. Essential for the asymmetric development of membrane domains of polarized epithelial cells. One or more isoforms may play a role in graft rejection. 12 isoforms of the human protein are produced by alternative promoter. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, CAMK; EC 2.7.11.26; EC 2.7.11.1; CAMK group; CAMKL family; MARK subfamily
Cellular Component: membrane; plasma membrane; actin filament; nucleus; basal cortex; lateral plasma membrane
Molecular Function: protein serine/threonine kinase activity; protein binding; tau-protein kinase activity; magnesium ion binding; lipid binding; ATP binding
Biological Process: establishment and/or maintenance of epithelial cell polarity; Wnt receptor signaling pathway; establishment of cell polarity; protein amino acid autophosphorylation; neuron migration; regulation of axonogenesis; protein amino acid phosphorylation; regulation of cytoskeleton organization and biogenesis
Reference #:  Q7KZI7 (UniProtKB)
Alt. Names/Synonyms: ELKL motif kinase 1; EMK-1; EMK1; MAP/microtubule affinity-regulating kinase 2; MARK2; MGC99619; PAR-1; PAR1 homolog; Par1b; Ser/Thr protein kinase PAR-1B; serine/threonine protein kinase EMK; Serine/threonine-protein kinase MARK2
Gene Symbols: MARK2
Molecular weight: 87,911 Da
Basal Isoelectric point: 9.73  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

MARK2

Protein Structure Not Found.

Substrate Sequence Logo
Sequence Logo

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Sites Implicated In
cell differentiation, altered: S212‑p
cytoskeletal reorganization: S212‑p
enzymatic activity, inhibited: S212‑p, T596‑p
intracellular localization: S400‑p, T596‑p
molecular association, regulation: S400‑p, T596‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 1 T6-p __MSSARtPLPTLNE
0 1 T20-p ERDTEQPtLGHLDsK
0 1 S26-p PtLGHLDsKPssKSN
0 2 S29-p GHLDsKPssKSNMIR
0 2 S30-p HLDsKPssKSNMIRG
0 18 S40-p NMIRGRNsAtsADEQ
0 3 T42-p IRGRNsAtsADEQPH
0 8 S43-p RGRNsAtsADEQPHI
0 3 Y53-p EQPHIGNyRLLKtIG
0 11 T58-p GNyRLLKtIGKGNFA
0 1 T87-p AVKIIDKtQLNSSSL
1 0 S91 IDKtQLNSSSLQKLF
1 0 S92 DKtQLNSSSLQKLFR
0 3 S197-p KIADFGFsNEFtFGN
0 1 T201-p FGFsNEFtFGNKLDt
6 69 T208-p tFGNKLDtFCGsPPY
5 18 S212-p KLDtFCGsPPYAAPE
0 1 S290-p KFLILNPsKRGTLEQ
1 0 T294 LNPsKRGTLEQIMKD
0 1 Y323-p YVEPLPDyKDPRRtE
0 1 T329-p DyKDPRRtELMVSMG
0 1 Y337-p ELMVSMGytREEIQD
0 1 T338-p LMVSMGytREEIQDS
0 1 Y351-p DSLVGQRyNEVMATy
1 0 T357 RyNEVMATyLLLGyK
0 2 Y358-p yNEVMATyLLLGyKs
0 1 Y363-p ATyLLLGyKsSELEG
0 2 S365-p yLLLGyKsSELEGDT
0 2 S380-p ITLKPRPsADLTNsS
0 1 T384 PRPsADLTNsSAPsP
0 1 S386-p PsADLTNsSAPsPSH
0 7 S390-p LTNsSAPsPSHKVQR
1 0 S400-p HKVQRSVsANPKQRR
0 2 F408 ANPKQRRFsDQAAGP
0 17 S409-p NPKQRRFsDQAAGPA
0 1 S420 AGPAIPTSNsYSKKT
0 4 S422-p PAIPTSNsYSKKTQS
0 5 Y423 AIPTSNsYSKKTQSN
0 1 T427 SNsYSKKTQSNNAEN
0 1 S429 sYSKKTQSNNAENKR
0 1 S448 RESGRKASsTAKVPA
0 3 S449-p ESGRKASsTAKVPAs
0 1 T450 SGRKASsTAKVPAsP
0 49 S456-p sTAKVPAsPLPGLER
0 7 T466-p PGLERKKttPtPstN
0 6 T467-p GLERKKttPtPstNS
0 4 T469-p ERKKttPtPstNSVL
0 3 S471-p KKttPtPstNSVLsT
0 2 T472-p KttPtPstNSVLsTs
0 1 S477-p PstNSVLsTsTNRsR
0 1 T478 stNSVLsTsTNRsRN
0 5 S479-p tNSVLsTsTNRsRNs
0 7 S483-p LsTsTNRsRNsPLLE
0 37 S486-p sTNRsRNsPLLERAs
0 5 S493-p sPLLERAsLGQAsIQ
0 3 S498-p RAsLGQAsIQNGKDS
0 1 S533-p RPRQHQKsMsASVHP
0 4 S535-p RQHQKsMsASVHPNK
0 15 S569-p PQRVPVAsPsAHNIs
0 16 S571-p RVPVAsPsAHNIsSs
0 1 S576-p sPsAHNIsSsGGAPD
0 1 S578-p sAHNIsSsGGAPDRT
0 3 S592-p TNFPRGVssRstFHA
0 2 S593-p NFPRGVssRstFHAG
0 8 S595-p PRGVssRstFHAGQL
4 5 T596-p RGVssRstFHAGQLR
0 31 Y613-p RDQQNLPyGVtPAsP
0 1 T616-p QNLPyGVtPAsPsGH
0 114 S619-p PyGVtPAsPsGHsQG
0 9 S621-p GVtPAsPsGHsQGRR
0 28 S624-p PAsPsGHsQGRRGAs
0 14 S631-p sQGRRGAsGsIFSkF
0 1 S633-p GRRGAsGsIFSkFTS
0 1 K637-ub AsGsIFSkFTSKFVR
0 1 T639 GsIFSkFTSKFVRRN
0 1 S640 sIFSkFTSKFVRRNL
0 3 S648-p KFVRRNLsFRFARRN
0 4 T667-p ESKDRVEtLRPHVVG
0 3 S675-p LRPHVVGsGGNDKEK
0 6 S692-p FREAKPRsLRFTWsM
0 1 T696 KPRsLRFTWsMKTTS
0 1 S698-p RsLRFTWsMKTTSSM
0 1 K716 EMMREIRKVLDANsC
0 1 S722-p RKVLDANsCQSELHE
4836 : Phospho-MARK Family (Activation Loop) Antibody
  MARK2 iso4  
T6 __MSSARTPLPTLNE
T20 ERDTEQPTLGHLDSK
S26 PTLGHLDSKPSSKSN
S29 GHLDSKPSSKSNMIR
S30 HLDSKPSSKSNMIRG
S40 NMIRGRNSATSADEQ
T42 IRGRNSATSADEQPH
S43 RGRNSATSADEQPHI
Y53 EQPHIGNYRLLKTIG
T58 GNYRLLKTIGKGNFA
T87 AVKIIDKTQLNSSSL
S91 IDKTQLNSSSLQKLF
S92 DKTQLNSSSLQKLFR
S197 KIADFGFSNEFTFGN
T201 FGFSNEFTFGNKLDt
T208-p TFGNKLDtFCGSPPY
S212 KLDtFCGSPPYAAPE
S290 KFLILNPSKRGTLEQ
T294 LNPSKRGTLEQIMKD
Y323 YVEPLPDYKDPRRTE
T329 DYKDPRRTELMVSMG
Y337 ELMVSMGYTREEIQD
T338 LMVSMGYTREEIQDS
Y351 DSLVGQRYNEVMATY
T357 RYNEVMATYLLLGYK
Y358 YNEVMATYLLLGYKS
Y363 ATYLLLGYKSSELEG
S365 YLLLGYKSSELEGDT
S380 ITLKPRPSADLTNSS
T384 PRPSADLTNSSAPSP
S386 PSADLTNSSAPSPSH
S390 LTNSSAPSPSHKVQR
S400 HKVQRSVSANPKQRR
F408 ANPKQRRFSDQAAGP
S409 NPKQRRFSDQAAGPA
S420 AGPAIPTSNSYSKKT
S422 PAIPTSNSYSKKTQS
Y423 AIPTSNSYSKKTQSN
T427 SNSYSKKTQSNNAEN
S429 SYSKKTQSNNAENKR
S448 RESGRKASSTAKVPA
S449 ESGRKASSTAKVPAS
T450 SGRKASSTAKVPASP
S456 STAKVPASPLPGLER
T466 PGLERKKTTPTPSTN
T467 GLERKKTTPTPSTNS
T469 ERKKTTPTPSTNSVL
S471 KKTTPTPSTNSVLST
T472 KTTPTPSTNSVLSTS
S477 PSTNSVLSTSTNRSR
T478 STNSVLSTSTNRSRN
S479 TNSVLSTSTNRSRNS
S483 LSTSTNRSRNSPLLE
S486 STNRSRNSPLLERAs
S493-p SPLLERAsLGQASIQ
S498 RAsLGQASIQNGKDS
- gap
- gap
S515-p PQRVPVAsPsAHNIS
S517-p RVPVAsPsAHNISSS
S522 sPsAHNISSSGGAPD
S524 sAHNISSSGGAPDRT
S538 TNFPRGVSSRSTFHA
S539 NFPRGVSSRSTFHAG
S541 PRGVSSRSTFHAGQL
T542 RGVSSRSTFHAGQLR
Y559 RDQQNLPYGVTPAsP
T562 QNLPYGVTPAsPSGH
S565-p PYGVTPAsPSGHsQG
S567 GVTPAsPSGHsQGRR
S570-p PAsPSGHsQGRRGAS
S577 sQGRRGASGSIFSKF
S579 GRRGASGSIFSKFTS
K583 ASGSIFSKFTSKFVR
T585 GSIFSKFTSKFVRRN
S586 SIFSKFTSKFVRRNL
- gap
T604 ESKDRVETLRPHVVG
S612 LRPHVVGSGGNDKEK
S629 FREAKPRSLRFTWSM
T633 KPRSLRFTWSMKTTS
S635 RSLRFTWSMKTTSSM
K653 EMMREIRKVLDANSC
S659 RKVLDANSCQSELHE
  MARK2 iso10  
- gap
- gap
- gap
- gap
- gap
S7 _MIRGRNSATSADEQ
T9 IRGRNSATSADEQPH
S10 RGRNSATSADEQPHI
Y20 EQPHIGNYRLLKTIG
T25 GNYRLLKTIGKGNFA
T54 AVKIIDKTQLNSSSL
S58 IDKTQLNSSSLQKLF
S59 DKTQLNSSSLQKLFR
S164 KIADFGFSNEFTFGN
T168 FGFSNEFTFGNKLDT
T175 TFGNKLDTFCGSPPY
S179 KLDTFCGSPPYAAPE
S257 KFLILNPSKRGTLEQ
T261 LNPSKRGTLEQIMKD
Y290 YVEPLPDYKDPRRTE
T296 DYKDPRRTELMVSMG
Y304 ELMVSMGYTREEIQD
T305 LMVSMGYTREEIQDS
Y318 DSLVGQRYNEVMATY
T324 RYNEVMATYLLLGYK
Y325 YNEVMATYLLLGYKS
Y330 ATYLLLGYKSSELEG
S332 YLLLGYKSSELEGDT
S347 ITLKPRPSADLTNSS
T351 PRPSADLTNSSAPSP
S353 PSADLTNSSAPSPSH
S357 LTNSSAPSPSHKVQR
S367 HKVQRSVSANPKQRR
F375 ANPKQRRFSDQAAGP
S376 NPKQRRFSDQAAGPA
S387 AGPAIPTSNSYSKKT
S389 PAIPTSNSYSKKTQS
Y390 AIPTSNSYSKKTQSN
T394 SNSYSKKTQSNNAEN
S396 SYSKKTQSNNAENKR
S415 RESGRKASSTAKVPA
S416 ESGRKASSTAKVPAS
T417 SGRKASSTAKVPASP
S423 STAKVPASPLPGLER
T433 PGLERKKTTPTPSTN
T434 GLERKKTTPTPSTNS
T436 ERKKTTPTPSTNSVL
S438 KKTTPTPSTNSVLST
T439 KTTPTPSTNSVLSTS
S444 PSTNSVLSTSTNRSR
T445 STNSVLSTSTNRSRN
S446 TNSVLSTSTNRSRNS
S450 LSTSTNRSRNSPLLE
S453 STNRSRNSPLLERAs
S460-p SPLLERAsLGQASIQ
S465 RAsLGQASIQNGKDS
- gap
- gap
S482-p PQRVPVAsPSAHNIS
S484 RVPVAsPSAHNISSS
S489 sPSAHNISSSGGAPD
S491 SAHNISSSGGAPDRT
S505 TNFPRGVSSRSTFHA
S506 NFPRGVSSRSTFHAG
S508 PRGVSSRSTFHAGQL
T509 RGVSSRSTFHAGQLR
Y526 RDQQNLPYGVTPASP
T529 QNLPYGVTPASPSGH
S532 PYGVTPASPSGHSQG
S534 GVTPASPSGHSQGRR
S537 PASPSGHSQGRRGAS
S544 SQGRRGASGSIFSKF
S546 GRRGASGSIFSKFTS
K550 ASGSIFSKFTSKFVR
T552 GSIFSKFTSKFVRRN
S553 SIFSKFTSKFVRRNL
S561 KFVRRNLSFRFARRP
- gap
S573 RRPHVVGSGGNDKEK
S590 FREAKPRSLRFTWSM
T594 KPRSLRFTWSMKTTS
S596 RSLRFTWSMKTTSSM
K614 EMMREIRKVLDANSC
S620 RKVLDANSCQSELHE
  MARK2 iso13  
- gap
- gap
- gap
- gap
- gap
S7 _MIRGRNSATSADEQ
T9 IRGRNSATSADEQPH
S10 RGRNSATSADEQPHI
Y20 EQPHIGNYRLLKTIG
T25 GNYRLLKTIGKGNFA
T54 AVKIIDKTQLNSSSL
S58 IDKTQLNSSSLQKLF
S59 DKTQLNSSSLQKLFR
S164 KIADFGFSNEFTFGN
T168 FGFSNEFTFGNKLDt
T175-p TFGNKLDtFCGSPPY
S179 KLDtFCGSPPYAAPE
S257 KFLILNPSKRGTLEQ
T261 LNPSKRGTLEQIMKD
Y290 YVEPLPDYKDPRRTE
T296 DYKDPRRTELMVSMG
Y304 ELMVSMGYTREEIQD
T305 LMVSMGYTREEIQDS
Y318 DSLVGQRYNEVMAtY
T324-p RYNEVMAtYLLLGYK
Y325 YNEVMAtYLLLGYKS
Y330 AtYLLLGYKSSELEG
S332 YLLLGYKSSELEGDT
S347 ITLKPRPSADLTNSS
T351 PRPSADLTNSSAPSP
S353 PSADLTNSSAPSPSH
S357 LTNSSAPSPSHKVQR
S367 HKVQRSVSANPKQRR
F375 ANPKQRRFsDQAGPA
S376-p NPKQRRFsDQAGPAI
S386 AGPAIPTSNsySKKT
S388-p PAIPTSNsySKKTQS
Y389-p AIPTSNsySKKTQSN
T393 SNsySKKTQSNNAEN
S395 sySKKTQSNNAENKR
S414 RESGRKASSTAKVPA
S415 ESGRKASSTAKVPAS
T416 SGRKASSTAKVPASP
S422 STAKVPASPLPGLER
T432 PGLERKKTTPTPSTN
T433 GLERKKTTPTPSTNS
T435 ERKKTTPTPSTNSVL
S437 KKTTPTPSTNSVLST
T438 KTTPTPSTNSVLSTS
S443 PSTNSVLSTSTNRSR
T444 STNSVLSTSTNRSRN
S445 TNSVLSTSTNRSRNS
S449 LSTSTNRSRNSPLLE
S452 STNRSRNSPLLERAS
S459 SPLLERASLGQASGL
S464 RASLGQASGLPPTEG
- gap
- gap
S489 PQRVPVASPSAHNIS
S491 RVPVASPSAHNISSS
S496 SPSAHNISSSGGAPD
S498 SAHNISSSGGAPDRT
S512 TNFPRGVSSRSTFHA
S513 NFPRGVSSRSTFHAG
S515 PRGVSSRSTFHAGQL
T516 RGVSSRSTFHAGQLR
Y533 RDQQNLPYGVTPAsP
T536 QNLPYGVTPAsPSGH
S539-p PYGVTPAsPSGHsQG
S541 GVTPAsPSGHsQGRR
S544-p PAsPSGHsQGRRGAS
S551 sQGRRGASGSIFSKF
S553 GRRGASGSIFSKFTS
K557 ASGSIFSKFTSKFVR
T559 GSIFSKFTSKFVRRN
S560 SIFSKFTSKFVRRNL
- gap
T578 ESKDRVETLRPHVVG
S586 LRPHVVGSGGNDKEK
S603 FREAKPRSLRFTWSM
T607 KPRSLRFTWSMKTTS
S609 RSLRFTWSMKTTSSM
K627 EMMREIRKVLDANSC
S633 RKVLDANSCQSELHE
  MARK2 iso14  
- gap
- gap
- gap
- gap
- gap
S7 _MIRGRNSATSADEQ
T9 IRGRNSATSADEQPH
S10 RGRNSATSADEQPHI
Y20 EQPHIGNYRLLKTIG
T25 GNYRLLKTIGKGNFA
T54 AVKIIDKTQLNSSSL
S58 IDKTQLNSSSLQKLF
S59 DKTQLNSSSLQKLFR
S164 KIADFGFSNEFTFGN
T168 FGFSNEFTFGNKLDt
T175-p TFGNKLDtFCGSPPY
S179 KLDtFCGSPPYAAPE
S257 KFLILNPSKRGTLEQ
T261 LNPSKRGTLEQIMKD
Y290 YVEPLPDYKDPRRTE
T296 DYKDPRRTELMVSMG
Y304 ELMVSMGYTREEIQD
T305 LMVSMGYTREEIQDS
Y318 DSLVGQRYNEVMATY
T324 RYNEVMATYLLLGYK
Y325 YNEVMATYLLLGYKS
Y330 ATYLLLGYKSSELEG
S332 YLLLGYKSSELEGDT
S347 ITLKPRPSADLTNSS
T351 PRPSADLTNSSAPSP
S353 PSADLTNSSAPSPSH
S357 LTNSSAPSPSHKVQR
S367 HKVQRSVSANPKQRR
F375 ANPKQRRFsDQAGPA
S376-p NPKQRRFsDQAGPAI
S386 AGPAIPTSNsySKKT
S388-p PAIPTSNsySKKTQS
Y389-p AIPTSNsySKKTQSN
T393 SNsySKKTQSNNAEN
S395 sySKKTQSNNAENKR
S414 RESGRKASSTAKVPA
S415 ESGRKASSTAKVPAS
T416 SGRKASSTAKVPASP
S422 STAKVPASPLPGLER
T432 PGLERKKTTPTPSTN
T433 GLERKKTTPTPSTNS
T435 ERKKTTPTPSTNSVL
S437 KKTTPTPSTNSVLST
T438 KTTPTPSTNSVLSTS
S443 PSTNSVLSTSTNRSR
T444 STNSVLSTSTNRSRN
S445 TNSVLSTSTNRSRNS
S449 LSTSTNRSRNSPLLE
S452 STNRSRNSPLLERAS
S459 SPLLERASLGQASIQ
S464 RASLGQASIQNGKDS
S499 RPRQHQKSMSASVHP
S501 RQHQKSMSASVHPNK
S535 PQRVPVASPSAHNIS
S537 RVPVASPSAHNISSS
S542 SPSAHNISSSGGAPD
S544 SAHNISSSGGAPDRT
S558 TNFPRGVSSRSTFHA
S559 NFPRGVSSRSTFHAG
S561 PRGVSSRSTFHAGQL
T562 RGVSSRSTFHAGQLR
Y579 RDQQNLPYGVTPAsP
T582 QNLPYGVTPAsPSGH
S585-p PYGVTPAsPSGHsQG
S587 GVTPAsPSGHsQGRR
S590-p PAsPSGHsQGRRGAS
S597 sQGRRGASGSIFSKF
S599 GRRGASGSIFSKFTS
K603 ASGSIFSKFTSKFVR
T605 GSIFSKFTSKFVRRN
S606 SIFSKFTSKFVRRNL
- gap
T624 ESKDRVETLRPHVVG
S632 LRPHVVGSGGNDKEK
S649 FREAKPRSLRFTWSM
T653 KPRSLRFTWSMKTTS
S655 RSLRFTWSMKTTSSM
K673 EMMREIRKVLDANSC
S679 RKVLDANSCQSELHE
  mouse

► Hide Isoforms
 
T6 __MSSARTPLPTLNE
T20 ERDTEQPTLGHLDSK
S26 PTLGHLDSKPSSKSN
S29 GHLDSKPSSKSNMLR
S30 HLDSKPSSKSNMLRG
S40-p NMLRGRNsATsADEQ
T42 LRGRNsATsADEQPH
S43-p RGRNsATsADEQPHI
Y53 EQPHIGNYRLLKtIG
T58-p GNYRLLKtIGKGNFA
T87 AVKIIDKTQLNSSSL
S91 IDKTQLNSSSLQKLF
S92 DKTQLNSSSLQKLFR
S197 KIADFGFSNEFTFGN
T201 FGFSNEFTFGNKLDt
T208-p TFGNKLDtFCGsPPY
S212-p KLDtFCGsPPYAAPE
S290 KFLILNPSKRGTLEQ
T294 LNPSKRGTLEQIMKD
Y323 YVEPLPDYKDPRRTE
T329 DYKDPRRTELMVSMG
Y337 ELMVSMGYTREEIQD
T338 LMVSMGYTREEIQDS
Y351 DSLVGQRYNEVMATY
T357 RYNEVMATYLLLGYK
Y358 YNEVMATYLLLGYKs
Y363 ATYLLLGYKsSELEG
S365-p YLLLGYKsSELEGDT
S380-p ITLKPRPsADLtNSS
T384-p PRPsADLtNSSAPsP
S386 PsADLtNSSAPsPSH
S390-p LtNSSAPsPSHKVQR
S400 HKVQRSVSANPKQRR
S408-p ANPKQRRssDQAVPA
S409-p NPKQRRssDQAVPAI
S419-p AVPAIPTsNsySKKt
S421-p PAIPTsNsySKKtQs
Y422-p AIPTsNsySKKtQsN
T426-p sNsySKKtQsNNAEN
S428-p sySKKtQsNNAENKR
S445-p EETGRKAsstAKVPA
S446-p ETGRKAsstAKVPAs
T447-p TGRKAsstAKVPAsP
S453-p stAKVPAsPLPGLDR
T463-p PGLDRKKttPAPsTN
T464-p GLDRKKttPAPsTNS
A466 DRKKttPAPsTNSVL
S468-p KKttPAPsTNSVLSt
T469 KttPAPsTNSVLSts
S474 PsTNSVLStsTNRsR
T475-p sTNSVLStsTNRsRN
S476-p TNSVLStsTNRsRNs
S480-p LStsTNRsRNsPLLD
S483-p sTNRsRNsPLLDRAs
S490-p sPLLDRAsLGQASIQ
S495 RAsLGQASIQNGKDS
S530 RPRQHQKSMsASVHP
S532-p RQHQKSMsASVHPNK
S566-p PQRVPVAsPsAHNIS
S568-p RVPVAsPsAHNISSS
S573 sPsAHNISSSSGAPD
S575 sAHNISSSSGAPDRT
S589 TNFPRGVSSRstFHA
S590 NFPRGVSSRstFHAG
S592-p PRGVSSRstFHAGQL
T593-p RGVSSRstFHAGQLR
Y610 RDQQNLPYGVTPAsP
T613 QNLPYGVTPAsPsGH
S616-p PYGVTPAsPsGHsQG
S618-p GVTPAsPsGHsQGRR
S621-p PAsPsGHsQGRRGAs
S628-p sQGRRGAsGSIFSKF
S630 GRRGAsGSIFSKFts
K634 AsGSIFSKFtsKFVR
T636-p GSIFSKFtsKFVRRN
S637-p SIFSKFtsKFVRRNL
- gap
T655-p ESKDRVEtLRPHVVG
S663-p LRPHVVGsGGTDKDK
S680-p FREAKPRsLRFtWSM
T684-gl KPRsLRFtWSMKTTS
S686 RsLRFtWSMKTTSSM
K704-ub EMMREIRkVLDANSC
S710 RkVLDANSCQSELHE
4836 : Phospho-MARK Family (Activation Loop) Antibody
  MARK2 iso3  
T6 __MSSARTPLPTLNE
T20 ERDTEQPTLGHLDSK
S26 PTLGHLDSKPSSKSN
S29 GHLDSKPSSKSNMLR
S30 HLDSKPSSKSNMLRG
S40 NMLRGRNSATSADEQ
T42 LRGRNSATSADEQPH
S43 RGRNSATSADEQPHI
Y53 EQPHIGNYRLLKTIG
T58 GNYRLLKTIGKGNFA
T87 AVKIIDKTQLNSSSL
S91 IDKTQLNSSSLQKLF
S92 DKTQLNSSSLQKLFR
S197 KIADFGFSNEFTFGN
T201 FGFSNEFTFGNKLDT
T208 TFGNKLDTFCGSPPY
S212 KLDTFCGSPPYAAPE
S290 KFLILNPSKRGTLEQ
T294 LNPSKRGTLEQIMKD
Y323 YVEPLPDYKDPRRTE
T329 DYKDPRRTELMVSMG
Y337 ELMVSMGYTREEIQD
T338 LMVSMGYTREEIQDS
Y351 DSLVGQRYNEVMATY
T357 RYNEVMATYLLLGYK
Y358 YNEVMATYLLLGYKS
Y363 ATYLLLGYKSSELEG
S365 YLLLGYKSSELEGDT
S380 ITLKPRPSADLTNSS
T384 PRPSADLTNSSAPSP
S386 PSADLTNSSAPSPSH
S390 LTNSSAPSPSHKVQR
S400 HKVQRSVSANPKQRR
S408 ANPKQRRSSDQAVPA
S409 NPKQRRSSDQAVPAI
S419 AVPAIPTSNSYSKKT
S421 PAIPTSNSYSKKTQS
Y422 AIPTSNSYSKKTQSN
T426 SNSYSKKTQSNNAEN
S428 SYSKKTQSNNAENKR
S445 EETGRKASSTAKVPA
S446 ETGRKASSTAKVPAS
T447 TGRKASSTAKVPASP
S453 STAKVPASPLPGLDR
T463 PGLDRKKTTPAPSTN
T464 GLDRKKTTPAPSTNS
A466 DRKKTTPAPSTNSVL
S468 KKTTPAPSTNSVLST
T469 KTTPAPSTNSVLSTS
S474 PSTNSVLSTSTNRSR
T475 STNSVLSTSTNRSRN
S476 TNSVLSTSTNRSRNS
S480 LSTSTNRSRNSPLLD
S483 STNRSRNSPLLDRAS
S490 SPLLDRASLGQASIQ
S495 RASLGQASIQNGKDS
- gap
- gap
S512 PQRVPVASPsAHNIS
S514-p RVPVASPsAHNISSS
S519 SPsAHNISSSSGAPD
S521 sAHNISSSSGAPDRT
S535 TNFPRGVSSRSTFHA
S536 NFPRGVSSRSTFHAG
S538 PRGVSSRSTFHAGQL
T539 RGVSSRSTFHAGQLR
Y556 RDQQNLPYGVTPASP
T559 QNLPYGVTPASPSGH
S562 PYGVTPASPSGHSQG
S564 GVTPASPSGHSQGRR
S567 PASPSGHSQGRRGAS
S574 SQGRRGASGSIFSKF
S576 GRRGASGSIFSKFTS
K580 ASGSIFSKFTSKFVR
T582 GSIFSKFTSKFVRRN
S583 SIFSKFTSKFVRRNL
- gap
T601 ESKDRVETLRPHVVG
S609 LRPHVVGSGGTDKDK
S626 FREAKPRSLRFTWSM
T630 KPRSLRFTWSMKTTS
S632 RSLRFTWSMKTTSSM
K650 EMMREIRKVLDANSC
S656 RKVLDANSCQSELHE
  rat

 
T6 __MSSARTPLPTLNE
T20 ERDTEQPTLGHLDSK
S26 PTLGHLDSKPSSKSN
S29 GHLDSKPSSKSNMLR
S30 HLDSKPSSKSNMLRG
S40-p NMLRGRNsATSADEQ
T42 LRGRNsATSADEQPH
S43 RGRNsATSADEQPHI
Y53-p EQPHIGNyRLLKTIG
T58 GNyRLLKTIGKGNFA
T87 AVKIIDKTQLNssSL
S91-p IDKTQLNssSLQKLF
S92-p DKTQLNssSLQKLFR
S197 KIADFGFSNEFTFGN
T201 FGFSNEFTFGNKLDt
T208-p TFGNKLDtFCGsPPY
S212-p KLDtFCGsPPYAAPE
S290 KFLILNPSKRGtLEQ
T294-p LNPSKRGtLEQIMKD
Y323 YVEPLPDYKDPRRTE
T329 DYKDPRRTELMVSMG
Y337 ELMVSMGYTREEIQD
T338 LMVSMGYTREEIQDS
Y351 DSLVGQRYNEVMATY
T357 RYNEVMATYLLLGYK
Y358 YNEVMATYLLLGYKs
Y363 ATYLLLGYKsSELEG
S365-p YLLLGYKsSELEGDT
S380 ITLKPRPSADLTNSS
T384 PRPSADLTNSSAPSP
S386 PSADLTNSSAPSPSH
S390 LTNSSAPSPSHKVQR
S400 HKVQRSVSANPKQRR
S408-p ANPKQRRssDQAVPA
S409-p NPKQRRssDQAVPAI
S419 AVPAIPTSNSYSKKT
S421 PAIPTSNSYSKKTQS
Y422 AIPTSNSYSKKTQSN
T426 SNSYSKKTQSNNAEN
S428 SYSKKTQSNNAENKR
S445 EETGRKASSTAKVPA
S446 ETGRKASSTAKVPAs
T447 TGRKASSTAKVPAsP
S453-p STAKVPAsPLPGLDR
T463 PGLDRKKTTPTPSTN
T464 GLDRKKTTPTPSTNS
T466 DRKKTTPTPSTNSVL
S468 KKTTPTPSTNSVLST
T469 KTTPTPSTNSVLSTS
S474 PSTNSVLSTSTNRsR
T475 STNSVLSTSTNRsRN
S476 TNSVLSTSTNRsRNs
S480-p LSTSTNRsRNsPLLD
S483-p STNRsRNsPLLDRAS
S490 sPLLDRASLGQASIQ
S495 RASLGQASIQNGKDS
- gap
- gap
S512-p PQRVPVAsPSAHNIS
S514 RVPVAsPSAHNISSS
S519 sPSAHNISSSSGAPD
S521 SAHNISSSSGAPDRT
S535 TNFPRGVSSRStFHA
S536 NFPRGVSSRStFHAG
S538 PRGVSSRStFHAGQL
T539-p RGVSSRStFHAGQLR
F556 RDQQNLPFGVTPAsP
T559 QNLPFGVTPAsPSGH
S562-p PFGVTPAsPSGHsQG
S564 GVTPAsPSGHsQGRR
S567-p PAsPSGHsQGRRGAS
S574 sQGRRGASGSIFSKF
S576 GRRGASGSIFSKFTS
K580 ASGSIFSKFTSKFVR
T582 GSIFSKFTSKFVRRN
S583 SIFSKFTSKFVRRNL
- gap
T601 ESKDRVETLRPHVVG
G609 LRPHVVGGGGTDKEK
S626 FREAKPRSLRFTWsM
T630 KPRSLRFTWsMKTTS
S632-p RSLRFTWsMKTTSSM
K650 EMMREIRKVLDANSC
S656 RKVLDANSCQSELHE
4836 : Phospho-MARK Family (Activation Loop) Antibody
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