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Protein Page:
CEACAM5 (human)

Overview
CEACAM5 Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily. CEA family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, GPI anchor; Membrane protein, integral; Immunoglobulin superfamily
Cellular Component: integral to plasma membrane; basolateral plasma membrane
Molecular Function: identical protein binding; protein homodimerization activity
Biological Process: homotypic cell-cell adhesion; negative regulation of apoptosis
Reference #:  P06731 (UniProtKB)
Alt. Names/Synonyms: Carcinoembryonic antigen; Carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CEA; CEACAM5; CEAM5; DKFZp781M2392; Meconium antigen 100
Gene Symbols: CEACAM5
Molecular weight: 76,795 Da
Basal Isoelectric point: 5.59  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

CEACAM5

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T199-p QLSNGNRtLtLFNVt
0 1 T201-p SNGNRtLtLFNVtRN
0 1 T206-p tLtLFNVtRNDTASy
0 1 Y213-p tRNDTASyKCETQNP
0 1 S226-p NPVSARRsDSVILNV
0 1 S404-p NKLSVDHsDPVILNV
0 1 T419-p LYGPDDPtIsPSYTY
0 1 S421-p GPDDPtIsPSYTYYR
0 1 S680-p TVSASGTsPGLSAGA
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