Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
NOV (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
NOV Immediate-early protein likely to play a role in cell growth regulation. Belongs to the CCN family. Expression is down-regulated by WT1. Interacts with FBLN1. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: extracellular matrix; intracellular membrane-bound organelle; cell soma; axon; dendrite; extracellular region
Molecular Function: insulin-like growth factor binding; growth factor activity
Biological Process: regulation of gene expression; regulation of cell growth
Reference #:  P48745 (UniProtKB)
Alt. Names/Synonyms: CCN family member 3; CCN3; IBP-9; IGF-binding protein 9; IGFBP-9; IGFBP9; Insulin-like growth factor-binding protein 9; nephroblastoma overexpressed gene; Nephroblastoma-overexpressed gene protein homolog; NOV; NOVH; Protein NOV homolog
Gene Symbols: NOV
Molecular weight: 39,162 Da
Basal Isoelectric point: 8.12  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

NOV

Protein Structure Not Found.


STRING  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UCSD-Nature  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T46-ga CPGRCPAtPPtCAPG
0 1 T49-ga RCPAtPPtCAPGVRA
0 1 S225-p KSCGMGFstRVTNRN
0 1 T226-p SCGMGFstRVTNRNR
0 1 S316-p IQAEFQCsPGQIVKK
0 1 T352-ga LQELELKttRGKM__
0 1 T353-ga QELELKttRGKM___
  mouse

 
I40 CPPKCPSISPTCAPG
T43 KCPSISPTCAPGVRS
S222 KSCGMGVSTRVTNRN
T223 SCGMGVSTRVTNRNR
L313 IQVEFQCLPGEIIKK
T349 LQDLELKTSRGEI__
S350 QDLELKTSRGEI___
  rat

 
I40 CPSQCPSISPTCAPG
T43 QCPSISPTCAPGVRS
S219 KSCGMGLSTRVTNRN
T220 SCGMGLSTRVTNRNL
L310 IQVEFQCLPGQIIKK
T346 LQELELKTSRGEM__
S347 QELELKTSRGEM___
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.