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Protein Page:
SLC17A7 (mouse)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
SLC17A7 Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family; Vesicle protein
Cellular Component: synaptic vesicle; neuron projection; membrane; synaptic vesicle membrane; presynaptic active zone; integral to membrane; intracellular organelle; excitatory synapse; synapse; cytoplasmic vesicle; cell junction
Molecular Function: sodium:inorganic phosphate symporter activity; symporter activity; sodium-dependent phosphate transmembrane transporter activity; inorganic phosphate transmembrane transporter activity
Biological Process: synaptic transmission, glutamatergic; response to stimulus; sodium ion transport; sequestering of neurotransmitter; L-glutamate import; synaptic transmission; phosphate transport; long-term memory; neurotransmitter transport; transport; ion transport; regulation of excitatory postsynaptic membrane potential; transmembrane transport
Reference #:  Q3TXX4 (UniProtKB)
Alt. Names/Synonyms: 2900052E22Rik; AI851913; Bnpi; Brain-specific Na(+)-dependent inorganic phosphate cotransporter; Slc17a7; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; Solute carrier family 17 member 7; Vesicular glutamate transporter 1; VGLU1; VGluT1
Gene Symbols: Slc17a7
Molecular weight: 61,637 Da
Basal Isoelectric point: 6.96  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

SLC17A7

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Modification Sites and Domains  
Click here to view other types of protein modifications

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       mouse

 
0 2 S36 GAETLELsADGRPVT
0 24 Y169 PSAARVHyGCVIFVR
0 7 Y187 GLVEGVTyPACHGIW
0 2 S281 IEDAIGEsAKLMNPV
0 1 T289 AKLMNPVtKFNtPWR
0 1 T293 NPVtKFNtPWRRFFT
0 1 S519 GHDQLAGsDEsEMED
0 1 S522 QLAGsDEsEMEDEAE
0 1 Y560 PPPPVRDy_______
  human

 
S36 GAETLELSADGRPVT
Y169 PSAARVHYGCVIFVR
Y187 GLVEGVTYPACHGIW
S281 IEDAIGESAKLMNPL
T289 AKLMNPLTKFSTPWR
T293 NPLTKFSTPWRRFFT
S519 GHDQLAGSDDSEMED
S522 QLAGSDDSEMEDEAE
Y560 PPPPVRDY_______
  rat

 
S36 GAETLELSADGRPVT
Y169 PSAARVHyGCVIFVR
Y187 GLVEGVTyPACHGIW
S281 IEDAIGESAKLMNPV
T289 AKLMNPVTKFNTPWR
T293 NPVTKFNTPWRRFFT
S519 GHDQLAGSDESEMED
S522 QLAGSDESEMEDEVE
Y560 PPPPVRDY_______
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