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SLC17A7
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. Note: This description may include information from UniProtKB.
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| Protein type: Transporter; Vesicle protein; Membrane protein, integral |
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Cellular Component: synaptic vesicle; neuron projection; membrane; synaptic vesicle membrane; presynaptic active zone; integral to membrane; intracellular organelle; excitatory synapse; synapse; cytoplasmic vesicle; cell junction
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Molecular Function: sodium:inorganic phosphate symporter activity; symporter activity; sodium-dependent phosphate transmembrane transporter activity; inorganic phosphate transmembrane transporter activity
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Biological Process: synaptic transmission, glutamatergic; response to stimulus; sodium ion transport; sequestering of neurotransmitter; L-glutamate import; synaptic transmission; phosphate transport; long-term memory; transport; neurotransmitter transport; ion transport; regulation of excitatory postsynaptic membrane potential; transmembrane transport
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Reference #:
Q3TXX4 (UniProtKB)
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| Alt. Names/Synonyms: 2900052E22Rik; AI851913; Bnpi; Brain-specific Na(+)-dependent inorganic phosphate cotransporter; Slc17a7; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; Solute carrier family 17 member 7; Vesicular glutamate transporter 1; VGLU1; VGluT1 |
| Gene Symbols: Slc17a7 |
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Molecular weight: 61,637 Da
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Basal Isoelectric point: 6.96
Predict pI for various phosphorylation states
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Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®
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