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Protein Page:
MEGF8 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
MEGF8 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Cellular Component: integral to membrane; nucleus
Molecular Function: protein binding; receptor activity; calcium ion binding
Biological Process: BMP signaling pathway; regulation of gene expression; epiboly involved in gastrulation with mouth forming second; positive regulation of axon extension involved in axon guidance; limb morphogenesis; cell migration involved in gastrulation; embryonic skeletal morphogenesis; embryonic limb morphogenesis
Reference #:  Q7Z7M0 (UniProtKB)
Alt. Names/Synonyms: C19orf49; EGF-like domain-containing protein 4; EGF-like protein 4; EGF-like-domain, multiple 4; EGFL4; Epidermal growth factor-like protein 4; FLJ22365; HBV pre-s2 binding protein 1; KIAA0817; MEGF8; MGC120684; MGC138147; multiple EGF-like domain protein 4; Multiple EGF-like domains protein 8; multiple EGF-like-domains 8; multiple epidermal growth factor-like domains 8; Multiple epidermal growth factor-like domains protein 8; Putative uncharacterized protein C19orf49; SBP1
Gene Symbols: MEGF8
Molecular weight: 303,100 Da
Basal Isoelectric point: 6.45  Predict pI for various phosphorylation states
Select Structure to View Below

MEGF8

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 9 S20-p LALAVLGsLSPGARA
0 1 Y85-p DTECTYDyLFVYDGD
0 1 S140-p FNASFRFsLCPGGCQ
0 1 S1169-p DCGCSFHsHCRKRGP
0 1 S1198-p CERCRPGsFGNATGS
0 1 Y1250-p QLCSPGYyGDPRAGG
0 1 S1258-p GDPRAGGsCFRECGG
0 1 T1353 GFPRFLDTGVVQSDR
0 1 S1749-p VPGEQPGsWGFREVR
0 1 S1790-p RPRLFHAsALLGDtM
0 1 T1796-p AsALLGDtMVVLGGR
0 1 R2023-m1 FKRTGETrRILSVQP
0 1 S2280-p CRNHTKGsHCEQCLP
0 1 S2836 AGRKGLLSQDNLTSM
  mouse

 
P20 LALAVLGPLSLRVLA
Y85 DTECTYDYLFVYDGD
S140 FNASFRFSLCPGGCQ
S1169 DCGCSFHSHCRRRGP
S1198 CERCRPGSFGNATGS
Y1250 QICSPGYYGDPRAGG
S1258 GDPRAGGSCFRECGG
T1353 GFPRFLDTGVVQSDR
- gap
S1734 RPRLFHASALLGDTM
T1740 ASALLGDTMVVLGGR
R1967 FKRTGETRRILSVQP
S2224 CRNHTKGSHCEQCLP
S2780-p GGRKGLLsQDNLTSM
  rat

 
P20 LAFAVLGPLSHKVLA
Y85 DTECTYDYLFVYDGD
S140 FNASFRFSLCPGGCQ
S1169 DCGCNFHSHCRRRGP
S1198 CERCRPGSFGNATGS
Y1250 QICSPGYYGDPRAGG
S1258 GDPRAGGSCFRECGG
T1353-p GFPRFLDtGVVQSDR
- gap
S1733 RPRLFHASALLGDTM
T1739 ASALLGDTMVVLGGR
R1966 FKRTGETRRILSVQP
S2223 CRNHTKGSHCEQCLP
S2779 GGRKGLLSQDNLTSM
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