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BORA (human)

Overview BORA Required for the activation of AURKA at the onset of mitosis. Interacts with AURKA. Belongs to the BORA family. Note: This description may include information from UniProtKB. Protein type: Activator protein Molecular Function: protein binding; protein kinase binding Biological Process: mitosis; regulation of protein localization; cell division; regulation of mitosis Reference #:  Q6PGQ7 (UniProtKB) Alt. Names/Synonyms: aurora borealis; BORA; C13orf34; chromosome 13 open reading frame 34; FLJ22624; HsBora; Protein aurora borealis Gene Symbols: BORA Molecular weight: 61,203 Da Basal Isoelectric point: 4.8  Predict pI for various phosphorylation states CST Pathways:  Cell Cycle: G2/M DNA Damage Checkpoint Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below BORA

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	Sites Implicated In
cell cycle regulation: S497‑p, T501‑p molecular association, regulation: S252‑p, S497‑p, T501‑p protein degradation: S497‑p, T501‑p

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		Y31-p	PFESPSDySNLHEQt
0	1		T38-p	ySNLHEQtLAsPSVF
0	1		S41-p	LHEQtLAsPSVFKST
0	3		T52-p	FKSTKLPtPGKFRWS
0	1		Y82-p	DIHRQALyLSHSRID
0	1		K95-a	IDKDVEDkRQkAIEE
0	1		K98-a	DVEDkRQkAIEEFFT
0	1		K106-a	AIEEFFTkDVIVPSP
0	1		S137-p	CTNINSDsPVGKKLT
0	1		S183-p	ADEFADQsPGNLsSS
0	1		S188-p	DQsPGNLsSSsLRRK
0	2		S191-p	PGNLsSSsLRRKLFL
0	2		S239-p	LSPVKCRsPLQTPSS
1	1		S252-p	SSGQFSSsPIQASAK
0	1		S270-p	LGSITSPsPISsPTF
1	0		S274-p	TSPsPISsPTFsPIE
1	0		S278-p	PISsPTFsPIEFQIG
0	1		T296-p	LSEQRKFtVHsPDAs
0	4		S299-p	QRKFtVHsPDAsSGT
0	2		S303-p	tVHsPDAsSGTNSNG
0	1		S318-p	ITNPCIRsPYIDGCs
0	3		S325-p	sPYIDGCsPIKNWSP
0	1		K328	IDGCsPIKNWSPMRL
0	1		S331	CsPIKNWSPMRLQMY
0	3		Q336	NWSPMRLQMYSGGTQ
0	1		T354	SVIQIPFTLETQGED
0	3		T407	VVTAMSVTQNQSSAS
0	2		S411	MSVTQNQSSASEKEL
0	1		T432-p	EREKDNNtVDMVDPI
2	0		S497-p	SSNIQMDsGYNtQNC
2	0		T501-p	QMDsGYNtQNCGSNI

	mouse
Y31	PFESPSDYSNLHEQT
T38	YSNLHEQTLASPSIF
S41	LHEQTLASPSIFKST
T52	FKSTKLPTPGKFRWS
Y82	EIHRQASYLRLSRID
K95	IDKDVEDKRQKAIEE
K98	DVEDKRQKAIEEFFT
K106	AIEEFFTKDVIVPSP
S137	CLSSHDDSPDGKKPS
T183	EEDFVAHTPGNLSSS
S188	AHTPGNLSSSSLRRK
S191	PGNLSSSSLRRKLFL
-	gap
S231	LEGQFSSSPIQNSVK
S250	GSVTTSPSAISSPTF
S254	TSPSAISSPTFSPIA
S258	AISSPTFSPIALQGG
T276	LSEPRKLTFHSPEAS
S279	PRKLTFHSPEASCAT
S283	TFHSPEASCATASTG
S298	IVNPSIRSPYIDGCs
S305-p	SPYIDGCsPIkNWsP
K308-a	IDGCsPIkNWsPRRL
S311-p	CsPIkNWsPRRLrGG
R316-m1	NWsPRRLrGGPQCLS
T331-p	SLVRIPFtLEAHSED
T368-p	VVTAMSVtQSHsGIA
S372-p	MSVtQSHsGIAEKER
T393	ESERENDTVDMVDPT
S458	SSAIQMNSDYNTQTC
T462	QMNSDYNTQTCVSNI

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