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Protein Page:
BORA (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
BORA Required for the activation of AURKA at the onset of mitosis. Interacts with AURKA. Belongs to the BORA family. Note: This description may include information from UniProtKB.
Protein type: Activator protein
Cellular Component: cytosol
Molecular Function: protein binding; protein kinase binding
Biological Process: mitosis; regulation of protein localization; regulation of mitosis; mitotic cell cycle; G2/M transition of mitotic cell cycle
Reference #:  Q6PGQ7 (UniProtKB)
Alt. Names/Synonyms: aurora borealis; BORA; C13orf34; chromosome 13 open reading frame 34; FLJ22624; HsBora; Protein aurora borealis
Gene Symbols: BORA
Molecular weight: 61,203 Da
Basal Isoelectric point: 4.8  Predict pI for various phosphorylation states
CST Pathways:  G2/M DNA Damage Checkpoint
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

BORA

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene


Sites Implicated In
cell cycle regulation: S274‑p, S278‑p, S497‑p, T501‑p
molecular association, regulation: S252‑p, S274‑p, S278‑p, S497‑p, T501‑p
protein degradation: S274‑p, S278‑p, S497‑p, T501‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 Y31-p PFESPSDySNLHEQT
1 2 S41-p LHEQTLAsPSVFKST
1 4 T52-p FKSTKLPtPGKFRWS
1 1 S112-p TKDVIVPsPWTDHEG
0 1 S183-p ADEFADQsPGNLsSS
0 1 S188-p DQsPGNLsSSsLRRK
0 3 S191-p PGNLsSSsLRRKLFL
0 3 S239-p LSPVKCRsPLQTPSS
1 2 S252-p SSGQFSSsPIQASAK
1 2 S270-p LGSITSPsPISsPTF
2 2 S274-p TSPsPISsPTFsPIE
2 2 S278-p PISsPTFsPIEFQIG
0 5 S299-p QRKFTVHsPDAsSGT
0 2 S303-p TVHsPDAsSGTNSNG
0 5 S325-p SPYIDGCsPIKNWSP
0 1 S331 CsPIKNWSPMRLQMY
0 4 Q336 NWSPMRLQMYSGGTQ
0 1 T354 SVIQIPFTLETQGED
0 3 T407 VVTAMSVTQNQSSAS
0 2 S411 MSVTQNQSSASEKEL
2 0 S497-p SSNIQMDsGYNtQNC
2 0 T501-p QMDsGYNtQNCGSNI
  mouse

 
Y31 PFESPSDYSNLHEQT
S41 LHEQTLASPSIFKST
T52 FKSTKLPTPGKFRWS
S112 TKDVIVPSPWTDHDG
T183 EEDFVAHTPGNLSSS
S188 AHTPGNLSSSSLRRK
S191 PGNLSSSSLRRKLFL
- gap
S231-p LEGQFSSsPIQNSVK
S250 GSVTTSPSAISSPTF
S254 TSPSAISSPTFSPIA
S258 AISSPTFSPIALQGG
S279 PRKLTFHSPEASCAT
S283 TFHSPEASCATASTG
S305-p SPYIDGCsPIKNWsP
S311-p CsPIKNWsPRRLrGG
R316-m1 NWsPRRLrGGPQCLS
T331-p SLVRIPFtLEAHSED
T368-p VVTAMSVtQSHsGIA
S372-p MSVtQSHsGIAEKER
S458 SSAIQMNSDYNTQTC
T462 QMNSDYNTQTCVSNI
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