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IL17RB (human)

Overview IL17RB Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB. Protein type: Membrane protein, integral Cellular Component: cell surface; membrane; integral to plasma membrane; cytoplasm; extracellular region Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity Biological Process: cytokine and chemokine mediated signaling pathway; defense response; regulation of cell growth Reference #:  Q9NRM6 (UniProtKB) Alt. Names/Synonyms: CRL4; cytokine receptor CRL4; Cytokine receptor-like 4; EVI27; I17RB; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B receptor; IL-17RB; IL-17Rh1; IL17BR; IL17RB; IL17Rh1; interleukin 17 receptor B; interleukin 17 receptor homolog 1; interleukin 17B receptor; Interleukin-17 receptor B; Interleukin-17B receptor; MGC5245 Gene Symbols: IL17RB Molecular weight: 55,885 Da Basal Isoelectric point: 8.44  Predict pI for various phosphorylation states CST Pathways:  PI3K/Akt Signaling

Select Structure to View Below IL17RB 3VBC - A=325-486 (mouse)

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	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		Y310-p	WVLVAGIyLMWRHER
0	1		K320	WRHERIKKtSFSTTT
0	1		T321-p	RHERIKKtSFSTTTL
0	1		Y447-p	LHKYVVVyFREIDTK
0	1		Y466-p	ALSVCPKyHLMKDAT

	mouse
Y306	WVLAAGIYLTWRQGR
K316-u	WRQGRSTkTSFPIST
T317	RQGRSTkTSFPISTM
Y444	LHKYLVVYLGGADLK
Y463	ALSVCPQYHLMKDAT

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