Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. Belongs to the methyltransferase superfamily. LCMT family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - histidine; Other Amino Acids Metabolism - selenoamino acid; EC 220.127.116.11; EC 2.1.1.-; Lipid Metabolism - androgen and estrogen; Amino Acid Metabolism - tyrosine; Methyltransferase
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.