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Protein Page:
CALB1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
CALB1 Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. Interacts with RANBP9. Belongs to the calbindin family. Note: This description may include information from UniProtKB.
Protein type: Calcium-binding protein
Chromosomal Location of Human Ortholog: 8q21.3
Cellular Component: cell soma; axon; dendrite; synapse; cytosol; nucleus
Molecular Function: vitamin D binding; protein binding; zinc ion binding; calcium ion binding
Biological Process: cytosolic calcium ion homeostasis; long-term memory; short-term memory; regulation of synaptic plasticity; locomotory behavior
Reference #:  P05937 (UniProtKB)
Alt. Names/Synonyms: CAB27; CALB; CALB1; Calbindin; calbindin 1, (28kD); calbindin 1, 28kDa; Calbindin D28; D-28K; RTVL-H protein; Vitamin D-dependent calcium-binding protein, avian-type
Gene Symbols: CALB1
Molecular weight: 30,025 Da
Basal Isoelectric point: 4.7  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

CALB1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S55-p KKAGLELsPEMKTFV
0 1 K59 LELsPEMKTFVDQYG
0 1 K109 EFMKTWRKYDTDHSG
0 1 K124 FIETEELKNFLKDLL
0 1 K128 EELKNFLKDLLEKAN
0 1 K142 NKTVDDTKLAEYTDL
0 1 K161 FDSNNDGKLELTEMA
0 1 K180 VQENFLLKFQGIKMC
0 1 K180 VQENFLLKFQGIKMC
0 1 K189 QGIKMCGKEFNkAFE
0 2 K193-ub MCGKEFNkAFELYDQ
0 1 K236 NNITTYKKNIMALSD
0 1 K246 MALSDGGKLYRTDLA
  mouse

 
S55 KKAGLELSPEMkSFV
K59-ub LELSPEMkSFVDQYG
K109-ub EFMKTWRkYDTDHSG
K124-ub FIETEELkNFLkDLL
K128-ub EELkNFLkDLLEKAN
K142-ub NKTVDDTkLAEYTDL
K161-ub FDSNNDGkLELTEMA
K180-ac VQENFLLkFQGIKMC
K180-ub VQENFLLkFQGIKMC
K189-ub QGIKMCGkEFNkAFE
K193-ub MCGkEFNkAFELYDQ
K236-ub NNITTYKkNIMALSD
K246-ub MALSDGGkLYRTDLA
  rat

 
S55-p KKAGLELsPEMKTFV
K59 LELsPEMKTFVDQYG
K109 EFMKTWRKYDTDHSG
K124 FIETEELKNFLKDLL
K128 EELKNFLKDLLEKAN
K142 NKTVDDTKLAEYTDL
K161 FDSNNDGKLELTEMA
K180 VQENFLLKFQGIKMC
K180 VQENFLLKFQGIKMC
K189 QGIKMCGKEFNKAFE
K193 MCGKEFNKAFELYDQ
K236 NNISTYKKNIMALSD
K246 MALSDGGKLYRTDLA
  chicken

 
T56 KKAGLDLTPEMKAFV
K60 LDLTPEMKAFVDQYG
K110 DFMQTWRKYDSDHSG
K125 FIDSEELKSFLKDLL
K129 EELKSFLKDLLQKAN
K143 NKQIEDSKLTEYTEI
K162 FDANNDGKLELTELA
K181 VQENFLIKFQGVKMC
K181 VQENFLIKFQGVKMC
K190 QGVKMCAKEFNKAFE
K194 MCAKEFNKAFEMYDQ
K237 NNLATYKKSIMALSD
K247 MALSDGGKLYRAELA
  cow

 
S55 KKAGLELSPEMKTFV
K59 LELSPEMKTFVDQYG
K109 EFMKTWRKYDTDHSG
K124 FIETEELKNFLKDLL
K128 EELKNFLKDLLEKAN
K142 NKTVDDTKLAEYTDL
K161 FDSNNDGKLELTEMA
K180 VQENFLLKFQGVKMC
K180 VQENFLLKFQGVKMC
K189 QGVKMCGKEFNKAFE
K193 MCGKEFNKAFELYDQ
K236 NNIPTYKKSIMALSD
K246 MALSDGGKLYRTDLA
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