May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. Interacts with DAXX. Binds DNA as a monomer. Binds TLE4. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 9p13
Cellular Component: nucleus
Molecular Function: protein binding; DNA binding; transcription factor activity
Biological Process: negative regulation of histone H3-K9 methylation; transcription from RNA polymerase II promoter; nervous system development; organ morphogenesis; multicellular organismal development; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; humoral immune response
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.