Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
DNAH9 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
DNAH9 Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Belongs to the dynein heavy chain family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Microtubule binding protein; Motor protein; Motility/polarity/chemotaxis
Cellular Component: microtubule; cilium axoneme; axonemal dynein complex; cytoskeleton; cytoplasm
Molecular Function: ATPase activity; motor activity; microtubule motor activity; ATP binding
Biological Process: cell projection organization and biogenesis; spermatogenesis; cell motility; microtubule-based movement
Reference #:  Q9NYC9 (UniProtKB)
Alt. Names/Synonyms: Axonemal beta dynein heavy chain 9; Ciliary dynein heavy chain 9; DNAH17L; DNAH9; DNAH9 variant protein; Dnahc9; DNAL1; DNEL1; DYH9; Dynein heavy chain 9, axonemal; dynein, axonemal, heavy chain 9; dynein, axonemal, heavy polypeptide 17-like; dynein, axonemal, heavy polypeptide 9; HL-20; HL20; KIAA0357
Gene Symbols: DNAH9
Molecular weight: 511,877 Da
Basal Isoelectric point: 5.64  Predict pI for various phosphorylation states
Select Structure to View Below

DNAH9
Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  DISEASE  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 1 S192-p LLPLPAGsEKMEFAD
0 1 S225-p ESAVIKWsYQVQVVL
0 1 Q481 ALSQQVQQMHEEFQE
0 3 Y567-p ARDTSDKyLVLIQMF
0 3 Y648-p GKRMQQKyEDMLSLL
0 1 S702-p NFNPQLIsVLKEMsY
0 1 S708-p IsVLKEMsYLEPREM
0 1 H717 LEPREMKHMPETAAA
0 1 Y849 RHDRMEKYYNLIKES
0 1 Y850 HDRMEKYYNLIKESG
0 1 N851 DRMEKYYNLIKESGL
0 1 R995-m2 MRRTLMErVQRMMGL
0 1 K1128-a NLDAFIKkSESGLLk
0 1 K1135-a kSESGLLkkVEKGDF
0 1 K1136-a SESGLLkkVEKGDFQ
0 1 T1442 KTLKELQTTWAGMEF
0 1 T1443 TLKELQTTWAGMEFQ
0 1 G1446 ELQTTWAGMEFQYEP
0 2 T1759-p KQVAQLKtLItMLIG
0 1 T1762-p AQLKtLItMLIGQLs
0 1 S1769-p tMLIGQLsKGDRQKI
0 1 R1842 EYLGNTPRLVITPLT
0 1 T2155-p FVVGGAGtGKsQVLR
0 1 S2158-p GGAGtGKsQVLRSLH
0 1 S2207 EWKDGLFSSIMRELA
0 1 S2208 WKDGLFSSIMRELAN
0 1 K2484 VGTAGTGKSVLVGAK
0 1 T2733-p DLFDKIQtEVLKKTF
0 1 T3415-p PYLSQLKtPIPVtPA
0 1 T3420-p LKtPIPVtPALDPLR
0 1 Y3864-p MRPDRMTyALRDFVE
0 1 Q3927 LGYTFNNQNFHNVSL
0 1 S4473-p LKTKENPsKWVLAGV
  mouse

 
S190 LLPLPVGSEKLEFVD
S223 ESAVIKWSHQVQVVL
R479-m1 SLSQKVQrMHEEFEE
Y565 AQDVSQKYLALIRMF
Y646 GKRMIQKYEDLLSLL
S700 NFNPQLISVLKEMNY
N706 ISVLKEMNYLQPSEV
T715-p LQPSEVKtIPETAAA
Y847-p QQDHMEKyysLIQES
Y848-p QDHMEKyysLIQESG
S849-p DHMEKyysLIQESGL
R993 LRSVLMERVQNMMTL
S1126 DLDSFIRSTESGLLK
K1133 STESGLLKRVEKGDF
R1134 TESGLLKRVEKGDFQ
T1440-p KTLKELQttWAsMEF
T1441-p TLKELQttWAsMEFQ
S1444-p ELQttWAsMEFQYES
T1757 KQVAQLKTLITMLIG
T1760 AQLKTLITMLIGPLS
S1767 TMLIGPLSKGDRQKI
R1840-m1 EYLGNTPrLVITPLT
T2153 FVVGGAGTGKSQVLR
S2156 GGAGTGKSQVLRSLH
S2205-p EWKDGLFssIMRELA
S2206-p WKDGLFssIMRELAI
K2482-a VGPAGSGkSVLVGAK
T2731 NLFDKIQTEFLKKNF
V3413 PYLSQLKVPIPTTPT
T3418 LKVPIPTTPTLDPLR
Y3862 MRPDRMTYAMRDFVE
R3925 LGYTFNNRNFHNVSL
S4471 LKTKENPSKWVLAGV
  rat

 
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
T229 FIVGGAGTGKSQVLK
S232 GGAGTGKSQVLKSLH
S281 EWKDGLFSSIMRELA
S282 WKDGLFSSIMRELAN
K558 VGSAGSGKSVLVGAK
T807 NLFDKLQTEFLKKNF
V1489 PYLSQLKVPIPTTPT
T1494 LKVPIPTTPTLDPLK
Y1938 MRPDRMTYAMRDFVE
R2001-m1 LGYTFNNrNFHNVSL
S2547 LKTKENPSKWVLAGV
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.