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Protein Page:
LAMP1 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
LAMP1 Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Cellular Component: lysosome; integral to plasma membrane; lysosomal membrane; dendrite; lamellar body; multivesicular body; cell soma; membrane; late endosome; melanosome; endosome membrane; sarcolemma; external side of plasma membrane
Biological Process: autophagic cell death; autophagy
Reference #:  P11279 (UniProtKB)
Alt. Names/Synonyms: CD107 antigen-like family member A; CD107a; LAMP-1; LAMP1; LAMPA; LGP120; lysosomal-associated membrane protein 1; Lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1
Gene Symbols: LAMP1
Molecular weight: 44,882 Da
Basal Isoelectric point: 9  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

LAMP1
Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 1 S27-p LGLMHCAsAAMFMVK
0 1 S69-p NMTFDLPsDAtVVLN
0 1 T72-p FDLPsDAtVVLNRss
0 1 S78-p AtVVLNRssCGKENt
0 1 S79-p tVVLNRssCGKENtS
0 1 T85-p ssCGKENtSDPSLVI
0 1 T230-p NVSGTNGtCLLASMG
0 1 K247 LNLTYERKDNTTVTR
0 1 K319-u DARDPAFkAANGSLR
0 3 Y336-p QATVGNSyKCNAEEH
0 1 S351-p VRVTKAFsVNIFKVW
0 11 Y414-p RKRSHAGyQTI____
  mouse

 
S23 AGLAHGASALFEVKN
- gap
- gap
S72 AEVLKNGSSCGKENV
S73 EVLKNGSSCGKENVS
V79 SSCGKENVSDPSLTI
T221 NVTGNNGTCLLASMA
K238-a LNITYLKkDNKTVTR
S308 DALVPTFSISNHSLK
Y325 QATVGNSYKCNTEEH
S340 IFVSKMLSLNVFSVQ
Y403 RKRSHAGYQTI____
  rat

 
P23 AGLAHSAPALFEVKD
- gap
- gap
S73 AEVLKNSSSCGEKNA
S74 EVLKNSSSCGEKNAS
A80 SSCGEKNASEPTLAI
T222 NVTGDNGTCLLASMA
K239 LNITYMKKDNTTVTR
S309 DAIEPTFSTSNYSLK
Y326 QASVGNSYKCNSEEH
A341 IFVSKALALNVFSVQ
Y404 RKRSHAGYQTI____
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