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KIF3B (human)

Overview KIF3B Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Belongs to the kinesin-like protein family. Kinesin II subfamily. Note: This description may include information from UniProtKB. Protein type: Motor protein; Microtubule binding protein Cellular Component: plus-end kinesin complex; centrosome; spindle microtubule; kinesin II complex; cytosol Molecular Function: protein binding; Rho GTPase binding; plus-end-directed microtubule motor activity; microtubule motor activity; ATP binding Biological Process: mitotic centrosome separation; mitotic spindle organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; anterograde axon cargo transport; determination of left/right symmetry; microtubule-based movement Reference #:  O15066 (UniProtKB) Alt. Names/Synonyms: HH0048; KIAA0359; KIF3B; kinesin family member 3B; Kinesin-like protein KIF3B; Microtubule plus end-directed kinesin motor 3B Gene Symbols: KIF3B Molecular weight: 85,125 Da Basal Isoelectric point: 7.3  Predict pI for various phosphorylation states

Select Structure to View Below KIF3B 3B6U - A/B=6-359 (human)

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB  |  Phospho3D  |  DISEASE  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		S122-p	KRGVIPNsFDHIFTH
0	1		S157-p	EEIRDLLsKDQTKRL
0	1		S180-p	GVYVKDLsSFVTKSV
0	1		Y675-p	PSRTTRDyEGPAIAP
0	5		A681	DyEGPAIAPKVQAAL
0	2		K714-a	STANKKSkARPKSGR
0	1		Y738-p	GTPASQLyPQsRGLV
0	1		S741-p	ASQLyPQsRGLVPK_

	mouse
S122	KRGVIPNSFDHIFTH
S157	EEIRDLLSKDQTKRL
S180	GVYVKDLSSFVTKSV
Y675	PSRTTRDYEGPAIsP
S681-p	DYEGPAIsPKVQAAL
K714	STASRKPKARPKSGR
Y738	GNPASQFYPQSRGLV
S741	ASQFYPQSRGLVPK_

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