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Protein Page:
RECQL5 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
RECQL5 May have an important role in DNA metabolism. Interacts with TOP3A and TOP3B. Ubiquitous. Belongs to the helicase family. RecQ subfamily. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA repair, damage; EC 3.6.1.-; Helicase; EC 3.6.4.12
Cellular Component: nucleoplasm; nuclear membrane; cytoplasm; nucleolus; DNA-directed RNA polymerase II, holoenzyme; nucleus
Molecular Function: DNA helicase activity; nucleic acid binding; ATP-dependent helicase activity; ATP binding
Biological Process: mitosis; DNA replication; DNA repair; DNA metabolic process; DNA duplex unwinding; chromosome separation; DNA recombination
Reference #:  O94762 (UniProtKB)
Alt. Names/Synonyms: ATP-dependent DNA helicase Q5; DNA helicase, RecQ-like type 5; FLJ90603; RecQ protein 5; RecQ protein-like 5; RECQ5; RECQL5
Gene Symbols: RECQL5
Molecular weight: 108,858 Da
Basal Isoelectric point: 8.86  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

RECQL5

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB  |  ENZYME  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 2 S2 ______MSSHHTTFP
0 1 F8 MSSHHTTFPFDPERR
0 1 K22-u RVRSTLKkVFGFDSF
0 2 T456-p RSSSWSKtCIGPsQG
0 2 S461-p SKtCIGPsQGNGFDP
0 4 S488-p FSRYDEGsGGsGDEG
0 3 S491-p YDEGsGGsGDEGRDE
0 1 V526 DPKIEEFVPPDENCP
0 7 S727-p SAHYGGPsPEKKAKS
0 4 S774 FFCRRVESPALLASA
0 4 S815-p EDGAGGHsPAPPQTE
0 5 T839-p CPPRDQGtPEVQPTP
  mouse

 
S2-p ______MsARPFStP
T8-p MsARPFStPFDRERR
K22 RVRSTLKKVFGFDSF
T457 RSSSWSKTCIGPSQG
S462 SKTCIGPSQGNGFDP
S489 FSRYDEGSGGSGDEG
S492 YDEGSGGSGDEGRDE
T527-p EPKIEEFtPPDEDCP
S728-p SVNCGDPsPEKKTKG
S773-p FLCQRTEsPPLPASV
L807 EVGAQGHLVAVFQTE
F830 CSLRDQSFPEGQPSP
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