May have an important role in DNA metabolism. Interacts with TOP3A and TOP3B. Ubiquitous. Belongs to the helicase family. RecQ subfamily. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Helicase; DNA repair, damage; EC 18.104.22.168; EC 3.6.1.-
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.