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Protein Page:
ACPP (human)

Overview
ACPP A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Belongs to the histidine acid phosphatase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.3.5; Phosphatase; EC 3.1.3.2; Cofactor and Vitamin Metabolism - riboflavin; Motility/polarity/chemotaxis
Cellular Component: multivesicular body; extracellular space; Golgi cisterna; lysosomal membrane; apical part of cell; integral to membrane; plasma membrane; vesicle membrane; intracellular; secretory granule; filopodium
Molecular Function: 5'-nucleotidase activity; choline binding; identical protein binding; acid phosphatase activity; protein binding; protein homodimerization activity; phosphoric monoester hydrolase activity; thiamin phosphate phosphatase activity
Biological Process: thiamin metabolic process; dephosphorylation; positive regulation of adenosine receptor signaling pathway; nucleotide metabolic process; regulation of sensory perception of pain; adenosine metabolic process; purine base metabolic process
Reference #:  P15309 (UniProtKB)
Alt. Names/Synonyms: acid phosphatase, prostate; ACP-3; ACP3; ACPP; PAP; PPAP; Prostatic acid phosphatase; prostatic acid phosphotase
Gene Symbols: ACPP
Molecular weight: 44,566 Da
Basal Isoelectric point: 5.83  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ACPP

Protein Structure Not Found.


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