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Protein Page:
MMP7 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
MMP7 Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. Belongs to the peptidase M10A family. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; EC 3.4.24.23; Protease; Secreted
Cellular Component: proteinaceous extracellular matrix; extracellular space; extracellular region
Molecular Function: zinc ion binding; metalloendopeptidase activity
Biological Process: response to drug; collagen catabolic process; extracellular matrix disassembly; defense response to Gram-positive bacterium; extracellular matrix organization and biogenesis; proteolysis; defense response to Gram-negative bacterium; antibacterial peptide secretion; regulation of cell proliferation
Reference #:  P09237 (UniProtKB)
Alt. Names/Synonyms: Matrilysin; Matrin; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7 (matrilysin, uterine); Matrix metalloproteinase-7; MMP-7; MMP7; MPSL1; PUMP-1; Pump-1 protease; PUMP1; uterine matrilysin; Uterine metalloproteinase
Gene Symbols: MMP7
Molecular weight: 29,677 Da
Basal Isoelectric point: 7.73  Predict pI for various phosphorylation states
CST Pathways:  Angiogenesis  |  GPCR Signaling to MAPKs
Select Structure to View Below

MMP7

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S47-p KRFYLYDsEtKNANS
0 1 T49-p FYLYDsEtKNANSLE
0 1 K84-ac RVIEIMQkPRCGVPD
  mouse

 
S47 RKFYPHDSKTKKVNS
T49 FYPHDSKTKKVNSLV
K84 YIMEIMQKPRCGVPD
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