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Protein Page:
GALK2 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
GALK2 Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. Belongs to the GHMP kinase family. GalK subfamily. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.1.157; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - galactose; Kinase, other
Cellular Component: cytoplasm
Molecular Function: galactokinase activity; N-acetylgalactosamine kinase activity; ATP binding
Biological Process: carbohydrate metabolic process; carbohydrate phosphorylation; galactose metabolic process
Reference #:  Q01415 (UniProtKB)
Alt. Names/Synonyms: Galactokinase 2; GALK2; GalNAc kinase; GK2; MGC1745; N-acetylgalactosamine kinase
Gene Symbols: GALK2
Molecular weight: 50,378 Da
Basal Isoelectric point: 6.19  Predict pI for various phosphorylation states
Select Structure to View Below

GALK2

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 4 S5-p ___MATEsPATRRVQ
0 1 K35-ub SKFGSIPkFYVRAPG
0 1 K168-ub VLGRNLSkVELAEIC
0 1 S208 TAKLIEFSPLRATDV
0 1 K234-ac NSCVEMNkAATSHFN
0 1 K252 MECRLAAKLLAkYKS
0 1 K256-ub LAAKLLAkYKSLQWD
0 1 K327 TQDVLIFKLYQRAkH
0 16 K333-ub FKLYQRAkHVySEAA
0 1 Y336-p YQRAkHVySEAARVL
0 1 S419-p VPADKLPsFLANVHK
0 1 K440-ub DGSLAPEkQSLFATK
0 1 K447 kQSLFATKPGGGALV
  mouse

 
D5 ___MAAEDPATRRVQ
K35 SKFGSTPKFYVRAPG
K168 VLGLRLSKVELAEIC
S208-p TAKLIEFsPLRATNV
K234 NSCMEMNKAATSHFN
K252-ub MECRLAAkVLAKHKG
K256 LAAkVLAKHKGLQWD
K327-ub TQDELTFkLYQRAKH
K333 FkLYQRAKHVYSEAA
Y336 YQRAKHVYSEAARVL
S419 VPADMLSSFLASVHE
K440 TSRLAQEKHSLFATk
K447-ub KHSLFATkPGGGALV
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