mediates U snRNA export from the nucleus. Binds to 5' capped mRNA. Found in aU snRNA export complex with RNUXA/PHAX, CBP20, CBP80, RAN, XPO1 and m7G-capped RNA. Interaction with RNUXA/PHAX. Heterodimer with NCBP2. Is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, UPF3B, UPF2, THOC4 and/or REFBP2. Note: This description may include information from UniProtKB.
Protein type: RNA processing; Translation
Cellular Component: nucleoplasm; mRNA cap complex; ribonucleoprotein complex; cytosol; nucleus
Molecular Function: protein binding; DNA binding; RNA binding; RNA cap binding
Biological Process: transcription from RNA polymerase II promoter; spliceosomal snRNP biogenesis; viral reproduction; positive regulation of viral transcription; RNA splicing; histone mRNA metabolic process; positive regulation of mRNA 3'-end processing; mRNA metabolic process; nuclear mRNA splicing, via spliceosome; mRNA export from nucleus; mRNA capping; RNA metabolic process; RNA elongation from RNA polymerase II promoter; mRNA catabolic process, nonsense-mediated decay; RNA-mediated gene silencing; gene expression; nuclear mRNA cis splicing, via U2-type spliceosome; mRNA 3'-end processing; termination of RNA polymerase II transcription; mRNA cleavage; regulation of translational initiation
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.