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Protein Page:
ADRM1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
ADRM1 Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. Interacts with PSMD1, ubiquitin and UCHL5. Belongs to the ADRM1 family. Note: This description may include information from UniProtKB.
Protein type: Cell development/differentiation; Proteasome complex
Cellular Component: proteasome complex; membrane; integral to plasma membrane; cytoplasm; nucleolus; plasma membrane; nucleus
Molecular Function: protein binding; protease binding
Biological Process: RNA elongation from RNA polymerase II promoter; proteasome assembly
Reference #:  Q16186 (UniProtKB)
Alt. Names/Synonyms: 110 kDa cell membrane glycoprotein; adhesion regulating molecule 1; Adhesion-regulating molecule 1; ADRM1; ARM-1; ARM1; GP110; hRpn13; M(r) 110,000 surface antigen; MGC29536; Proteasomal ubiquitin receptor ADRM1; Proteasome regulatory particle non-ATPase 13; regulatory particle non-ATPase 13; Rpn13; Rpn13 homolog
Gene Symbols: ADRM1
Molecular weight: 42,153 Da
Basal Isoelectric point: 4.96  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ADRM1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 2 T2-p ______MtTSGALFP
0 1 T3 _____MtTSGALFPS
0 1 S4 ____MtTSGALFPSL
0 2 S15-p FPSLVPGsRGASNky
0 1 K21-ac GsRGASNkyLVEFRA
0 51 K21-ub GsRGASNkyLVEFRA
0 3 Y22-p sRGASNkyLVEFRAG
0 6 S32-p EFRAGKMsLkGTTVt
0 1 K34-m1 RAGKMsLkGTTVtPD
0 150 K34-ub RAGKMsLkGTTVtPD
0 1 T39-p sLkGTTVtPDkRKGL
0 1 K42-m1 GTTVtPDkRKGLVYI
0 27 K42-ub GTTVtPDkRKGLVYI
0 10 K62-ub SLIHFCWkDRTSGNV
0 13 K83-ac FPDDCEFkRVPQCPS
0 52 K83-ub FPDDCEFkRVPQCPS
0 2 K97-ub SGRVYVLkFKAGSKR
0 1 Y127-p HCRKVNEyLNNPPMP
0 1 S140-p MPGALGAsGssGHEL
0 1 S142-p GALGAsGssGHELSA
0 1 S143-p ALGAsGssGHELSAL
0 13 S211-p SSSSSSRsQsAAVtP
0 6 S213-p SSSSRsQsAAVtPSs
0 14 T217-p RsQsAAVtPSstTSS
0 2 S219 QsAAVtPSstTSSTR
0 3 S220-p sAAVtPSstTSSTRA
0 1 T221-p AAVtPSstTSSTRAT
0 1 S224 tPSstTSSTRATPAP
0 3 K379-ub GDVEAFAkAMQNNAk
0 5 K386-ub kAMQNNAkPEQkEGD
0 22 K390-ub NNAkPEQkEGDTkDk
0 3 K395-ub EQkEGDTkDkkDEEE
0 2 K397-ub kEGDTkDkkDEEEDM
0 8 K398-ub EGDTkDkkDEEEDMs
0 16 S405-p kDEEEDMsLD_____
  mouse

 
T2-p ______MttsGALFP
T3-p _____MttsGALFPS
S4-p ____MttsGALFPSL
S15-p FPSLVPGsRGSSTkY
K21 GsRGSSTKYLVEFRA
K21-ub GsRGSSTkYLVEFRA
Y22 sRGSSTkYLVEFRAG
S32 EFRAGKMSLkGTTVT
K34 RAGKMSLKGTTVTPD
K34-ub RAGKMSLkGTTVTPD
T39 SLkGTTVTPDkRKGL
K42 GTTVTPDKRKGLVYI
K42-ub GTTVTPDkRKGLVYI
K62 SLIHFCWKDRTSGTV
K83-ac FPDDCEFkRVPQCPS
K83 FPDDCEFKRVPQCPS
K97 SGRVYVLKFKAGSKR
C127 HCRKVNECLNNPPMP
S140 MPGSLGASGSSGHEL
S142 GSLGASGSSGHELSA
S143 SLGASGSSGHELSAL
S211-p SSSSSSRsQsAAVtP
S213-p SSSSRsQsAAVtPss
T217-p RsQsAAVtPssSTSs
S219-p QsAAVtPssSTSsAR
S220-p sAAVtPssSTSsARA
S221 AAVtPssSTSsARAT
S224-p tPssSTSsARATPAP
K379-ub GDVEAFAkAMQNNAK
K386 kAMQNNAKSDPKEGD
K390 NNAKSDPKEGDTkDK
K395-ub DPKEGDTkDKkDEEE
K397 KEGDTkDKkDEEEDM
K398-ub EGDTkDKkDEEEDMs
S405-p kDEEEDMsLD_____
  rat

 
T2 ______MTTSGALFP
T3 _____MTTSGALFPS
S4 ____MTTSGALFPSL
S15 FPSLVPGSRGSSTKY
K21 GSRGSSTKYLVEFRA
K21 GSRGSSTKYLVEFRA
Y22 SRGSSTKYLVEFRAG
S32 EFRAGKMSLkGTTVT
K34 RAGKMSLKGTTVTPD
K34-ub RAGKMSLkGTTVTPD
T39 SLkGTTVTPDKRKGL
K42 GTTVTPDKRKGLVYI
K42 GTTVTPDKRKGLVYI
K62 SLIHFCWKDRTSGTV
K83 FPDDCEFKRVPQCPS
K83 FPDDCEFKRVPQCPS
K97 SGRVYVLKFKAGSKR
C127 HCRKVNECLNNPPMP
S140 MPGTLGASGSSGHEL
S142 GTLGASGSSGHELSA
S143 TLGASGSSGHELSAL
S211 SSSSSSRSQSAAVTP
S213 SSSSRSQSAAVTPSS
T217 RSQSAAVTPSSTTSS
S219 QSAAVTPSSTTSSAR
S220 SAAVTPSSTTSSARA
T221 AAVTPSSTTSSARAT
S224 TPSSTTSSARATPAP
K379 GDVEAFAKAMQNNAK
K386 KAMQNNAKSDPKEGD
K390 NNAKSDPKEGDTKDK
K395 DPKEGDTKDKKDEEE
K397 KEGDTKDKKDEEEDM
K398 EGDTKDKKDEEEDMs
S405-p KDEEEDMsLD_____
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