Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. Interacts with PSMD1, ubiquitin and UCHL5. Belongs to the ADRM1 family. Note: This description may include information from UniProtKB.
Protein type: Cell development/differentiation; Proteasome complex
Chromosomal Location of Human Ortholog: 20q13.33
Cellular Component: proteasome complex; membrane; integral to plasma membrane; cytoplasm; nucleolus; plasma membrane; nucleus
Molecular Function: protein binding; protease binding
Biological Process: RNA elongation from RNA polymerase II promoter; proteasome assembly
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.