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Protein Page:
PHACTR1 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
PHACTR1 Belongs to the phosphatase and actin regulator family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Cellular Component: synapse; nucleus; cytosol; cell junction
Molecular Function: protein phosphatase inhibitor activity; actin binding
Biological Process: actin cytoskeleton reorganization; actomyosin structure organization and biogenesis; cell motility involved in cell locomotion; stress fiber formation
Reference #:  Q9C0D0 (UniProtKB)
Alt. Names/Synonyms: dJ257A7.2; KIAA1733; MGC126575; MGC126577; PHACTR1; PHAR1; Phosphatase and actin regulator 1; RPEL; RPEL repeat containing 1; RPEL1
Gene Symbols: PHACTR1
Molecular weight: 66,308 Da
Basal Isoelectric point: 6.51  Predict pI for various phosphorylation states
Select Structure to View Below

PHACTR1

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 2 Y29 ESAQRFFYSQGAQAR
0 2 T39 GAQARRATLLLPPTL
0 4 S67-p IRRVRSKsDTPYLAE
0 1 S78 YLAEARISFNLGAAE
0 2 S97-p LAAMRSDsLVPGTHt
0 1 T102 SDsLVPGTHtPPIRR
0 7 T104-p sLVPGTHtPPIRRRS
0 2 S145 AALERKISMRQSREE
0 3 S237-p PCLPVKLsPPLPPKK
0 6 Y340 RVPCSTSYHSSGLHS
0 4 K353 HSGDGVTKAGPMGLP
0 1 S423 MKVCRKDSLAIKLSN
0 28 S467-p TKLTRRLsQRPtAEE
0 1 T471-p RRLsQRPtAEELEQR
0 2 S505-p RRLTRKLsQRPTVEE
0 6 Y525-p ILIRFSDyVEVADAQ
0 3 K550 TRLTAADKAAIRKEL
  mouse

► Hide Isoforms
 
Y29 ESAQRFFYSQGAQAR
T39-p GAQARRAtLLLPPTL
S67-p IRRVRSKsDTPYLAE
S78-p YLAEARIsFNLGAAE
S97-p LAAMRSDsLVPGtHt
T102-p SDsLVPGtHtPPIRR
T104-p sLVPGtHtPPIRRRS
S145-p AALERKIsMRQSREE
S237-p PCLPVKLsPPLPPKK
Y340 RVPCSTSYHSSGLHS
K353 HSSDGITKAGPMGLP
S423-p MKVCRKDsLAIKLSN
S467-p TKLTRRLsQRPTAEE
T471 RRLsQRPTAEELEQR
S505 RRLTRKLSQRPTVEE
Y525 ILIRFSDYVEVADAQ
K550 TRLTAADKAAIRKEL
  PHACTR1 iso4  
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S31 DFFRRRLSQRPTAEE
T35 RRLSQRPTAEELEQR
S69 RRLTRKLSQRPTVEE
Y89 ILIRFSDYVEVADAQ
K114 TRLTAADKAAIRKEL
  rat

 
Y29-p ESAQRFFySQGAQAR
T39 GAQARRATLLLPPTL
S67 IRRVRSKSDTPYLAE
S78 YLAEARISFNLGAAE
S97 LAAMRSDSLVPGTHT
T102 SDSLVPGTHTPPIRR
T104 SLVPGTHTPPIRRRS
S145 AALERKISMRQSREE
S237 PCLPVKLSPPLPPKK
Y340-p RVPCSTSyHSSGLHS
K353-u HSSDGVTkAGPLGLP
S423 MKVCRKDSLAIKLSN
S467-p TKLTRRLsQRPTAEE
T471 RRLsQRPTAEELEQR
S505-p RRLTRKLsQRPTVEE
Y525-p ILIRFSDyVEVADAQ
K550-u TRLTAADkAAIRKEL
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