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Protein Page:
BACH2 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
BACH2 Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK. Belongs to the bZIP family. CNC subfamily. Note: This description may include information from UniProtKB.
Protein type: DNA binding protein; Transcription factor
Cellular Component: cytoplasm; nucleus
Molecular Function: sequence-specific DNA binding; transcription factor activity
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
Reference #:  Q9BYV9 (UniProtKB)
Alt. Names/Synonyms: BACH2; BTB and CNC homolog 2; BTB and CNC homology 1, basic leucine zipper transcription factor 2; Transcription regulator protein BACH2
Gene Symbols: BACH2
Molecular weight: 92,537 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

BACH2

Protein Structure Not Found.


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Sites Implicated In
apoptosis, inhibited: S521‑p
cell growth, altered: S521‑p
transcription, altered: S521‑p
intracellular localization: S521‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S159-p PHEDCENsAGEEEDE
2 0 K202-sm AAIPVAEkEEALLPE
0 1 S220 PTDTKESSEKDALTQ
2 0 K276-sm GLARGQIkSEPPSEE
0 1 S294-p ESITLCLsGDEPDAK
0 4 S315-p EMDRKQPsPAPtPTA
0 1 T319-p KQPsPAPtPTAPAGA
0 1 A322 sPAPtPTAPAGAACL
0 1 A324 APtPTAPAGAACLER
0 2 S334-p ACLERSRsVAsPSCL
0 3 S337-p ERSRsVAsPSCLRSL
0 2 S409-p VSNFTMGsPLRGPGL
2 0 K421-sm PGLEALCkQEGELDR
0 8 S510-p PIKVCPRsPPLETRT
1 0 S521-p ETRTRTSsSCSsYsY
0 1 S525-p RTSsSCSsYsYAEDG
0 1 S527-p SsSCSsYsYAEDGSG
0 1 S533 YsYAEDGSGGSPCSL
0 2 S536 AEDGSGGSPCSLPLC
0 2 S539 GSGGSPCSLPLCEFs
0 1 S546-p SLPLCEFsSSPCsQG
0 1 S551-p EFsSSPCsQGARFLA
0 2 Y572-p GLMGDGMyNQVRPQI
2 0 K580-sm NQVRPQIkCEQSYGT
  mouse

► Hide Isoforms
 
S159 PQEDHGNSAGEEEEE
K201-sm TAIPVAEkEEALLPE
S219-p PTDTKENsEKGALTQ
K275-sm GLPMGQIkSEPPSEE
S293 ESITLCLSGDETDIK
S314-p EMDRKQPsPAPTPSt
T318 KQPsPAPTPStPtGA
T321-p sPAPTPStPtGAACL
T323-p APTPStPtGAACLDR
S333-p ACLDRSRsVSsPSCL
S336-p DRSRsVSsPSCLRSL
S408-p VSNFAMGsPLRGPGP
K420-sm PGPETLCkQEGELDR
S509 PIKVCPRSPPLETRT
S520 ETRTRTSSSCSSYSY
S524 RTSSSCSSYSYAEDG
S526 SSSCSSYSYAEDGsG
S532-p YSYAEDGsGGsPCsL
S535-p AEDGsGGsPCsLPLC
S538-p GsGGsPCsLPLCEFS
S545 sLPLCEFSSSPCSQG
S550 EFSSSPCSQGARFLA
Y571-p GLMGDGMyNQVRPQI
K579-sm NQVRPQIkCEQSYGT
  BACH2 iso2  
S159 PQEDHGNSAGEEEEE
K201 TAIPVAEKEEALLPE
S219 PTDTKENSEKGALTQ
K275 GLPMGQIKSEPPSEE
S293 ESITLCLSGDETDIK
S314-p EMDRKQPsPAPTPST
T318 KQPsPAPTPSTPTGA
T321 sPAPTPSTPTGAACL
T323 APTPSTPTGAACLDR
S333 ACLDRSRSVSSPSCL
S336 DRSRSVSSPSCLRSL
S408 VSNFAMGSPLRGPGP
K420 PGPETLCKFSSSPCS
- gap
- gap
- gap
- gap
- gap
- gap
- gap
S422 PETLCKFSSSPCSQG
S427 KFSSSPCSQGARFLA
Y448 GLMGDGMYNQVRPQI
K456 NQVRPQIKCEQSYGT
  rat

 
S159 PQEDHGNSAGEEEEE
K201 TAIPVAEKEEALLPE
S219 PTDTKENSEKGALTQ
K275 GLSVGQIKSEPPNEE
S293 ESITLCLSGDETDIK
S314 EMDRKQPSPAPPPGT
P318 KQPSPAPPPGTPTGA
T321 SPAPPPGTPTGATSL
- under review  
S333 TSLDRSRSVSSPSCL
S336 DRSRSVSSPSCLRSL
S408 VSNFAMGSPLRGPGP
K420 PGPETLCKQEGELDR
S509 PIKVCPRSPPLETRT
S520 ETRTRTSSSCSSYSY
S524 RTSSSCSSYSYAEDG
S526 SSSCSSYSYAEDGSG
S532 YSYAEDGSGGSPCSL
S535 AEDGSGGSPCSLPLC
S538 GSGGSPCSLPLCEFS
S545 SLPLCEFSSSPCSQG
S550 EFSSSPCSQGARFLA
Y571 GLMGDGMYNQVRPQI
K579 NQVRPQIKCEQSYGT
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