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Protein Page:
FABP1 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
FABP1 Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Note: This description may include information from UniProtKB.
Protein type: Lipid binding protein
Cellular Component: nucleoplasm; peroxisomal matrix; apical cortex; cytosol
Molecular Function: antioxidant activity; bile acid binding; phospholipid binding; drug binding; chromatin binding; long-chain fatty acid transporter activity; fatty acid binding
Biological Process: positive regulation of hydrolase activity; positive regulation of cell proliferation; cellular lipid metabolic process; negative regulation of caspase activity; positive regulation of fatty acid beta-oxidation; intestinal absorption; negative regulation of apoptosis
Reference #:  P07148 (UniProtKB)
Alt. Names/Synonyms: FABP1; FABPL; fatty acid binding protein 1, liver; Fatty acid-binding protein 1; Fatty acid-binding protein, liver; L-FABP; Liver-type fatty acid-binding protein
Gene Symbols: FABP1
Molecular weight: 14,208 Da
Basal Isoelectric point: 6.6  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

FABP1

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 2 K6 __MSFSGKYQLQsQE
0 1 K6 __MSFSGKYQLQsQE
0 4 S11-p SGKYQLQsQENFEAF
0 2 K20 ENFEAFMKAIGLPEE
0 2 K31 LPEELIQKGkDIKGV
0 1 K33-a EELIQKGkDIKGVSE
0 2 K36 IQKGkDIKGVSEIVQ
0 2 K36 IQKGkDIKGVSEIVQ
0 21 K46-a SEIVQNGkHFKFTIt
0 2 K46 SEIVQNGKHFKFTIt
0 1 K49 VQNGkHFKFTItAGS
0 2 T51 NGkHFKFTItAGSKV
0 2 T53-p kHFKFTItAGSKVIQ
0 2 A54 HFKFTItAGSKVIQN
0 1 S56 KFTItAGSKVIQNEF
0 1 K57 FTItAGSKVIQNEFT
0 1 T64 KVIQNEFTVGEECEL
0 1 K78 LETMTGEKVKTVVQL
0 2 K80 TMTGEKVKTVVQLEG
0 2 Q84 EKVKTVVQLEGDNKL
0 2 Q84 EKVKTVVQLEGDNKL
0 1 K90 VQLEGDNKLVTTFKN
0 1 K90 VQLEGDNKLVTTFKN
0 1 T94 GDNKLVTTFKNIKSV
0 2 K96 NKLVTTFKNIKSVTE
0 1 K96 NKLVTTFKNIKSVTE
0 1 K99 VTTFKNIKSVTELNG
0 2 K99 VTTFKNIKSVTELNG
0 3 S100 TTFKNIKSVTELNGD
0 11 K121-a TLGDIVFkRISKRI_
0 1 K121 TLGDIVFKRISKRI_
  mouse

 
K6-a __MNFSGkYQLQsQE
K6-u __MNFSGkYQLQsQE
S11-p SGkYQLQsQENFEPF
K20-u ENFEPFMkAIGLPED
K31-u LPEDLIQkGKDIkGV
K33 EDLIQkGKDIkGVSE
K36-a IQkGKDIkGVSEIVH
K36-u IQkGKDIkGVSEIVH
K46-a SEIVHEGkKIkLtIt
K46-u SEIVHEGkKIkLtIt
K49-u VHEGkKIkLtItyGP
T51-p EGkKIkLtItyGPkV
T53-p kKIkLtItyGPkVVR
Y54-p KIkLtItyGPkVVRN
P56 kLtItyGPkVVRNEF
K57-u LtItyGPkVVRNEFt
T64-p kVVRNEFtLGEECEL
K78-u LETMTGEkVkAVVkL
K80-u TMTGEkVkAVVkLEG
K84-a EkVkAVVkLEGDNkM
K84-u EkVkAVVkLEGDNkM
K90-a VkLEGDNkMVTtFkG
K90-u VkLEGDNkMVTtFkG
T94-p GDNkMVTtFkGIksV
K96-a NkMVTtFkGIksVTE
K96-u NkMVTtFkGIksVTE
K99-a VTtFkGIksVTELNG
K99-u VTtFkGIksVTELNG
S100-p TtFkGIksVTELNGD
K121-a TLGDIVYkRVSKRI_
K121-u TLGDIVYkRVSKRI_
  rat

 
K6 __MNFSGKYQVQsQE
K6 __MNFSGKYQVQsQE
S11-p SGKYQVQsQENFEPF
K20 ENFEPFMKAMGLPED
K31 LPEDLIQKGKDIKGV
K33 EDLIQKGKDIKGVSE
K36 IQKGKDIKGVSEIVH
K36 IQKGKDIKGVSEIVH
K46 SEIVHEGKKVKLTIT
K46 SEIVHEGKKVKLTIT
K49 VHEGKKVKLTITYGs
T51 EGKKVKLTITYGsKV
T53 KKVKLTITYGsKVIH
Y54 KVKLTITYGsKVIHN
S56-p KLTITYGsKVIHNEF
K57 LTITYGsKVIHNEFT
T64 KVIHNEFTLGEECEL
K78 LETMTGEKVKAVVKM
K80 TMTGEKVKAVVKMEG
K84 EKVKAVVKMEGDNKM
K84 EKVKAVVKMEGDNKM
K90 VKMEGDNKMVTTFKG
K90 VKMEGDNKMVTTFKG
T94 GDNKMVTTFKGIKSV
K96 NKMVTTFKGIKSVTE
K96 NKMVTTFKGIKSVTE
K99 VTTFKGIKSVTEFNG
K99 VTTFKGIKSVTEFNG
S100 TTFKGIKSVTEFNGD
K121 TLGDIVYKRVSKRI_
K121 TLGDIVYKRVSKRI_
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