a kinase of the PEK family. Phosphorylates and inhibits eukaryotic initiation factor (eIF)-2 alpha, providing an important protective mechanism during various cellular stress conditions including endoplasmic reticulum (ER) stress. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, Other; EC 126.96.36.199; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Translation; Other group; PEK family; GCN2 subfamily
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.