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Protein Page:
BCL2L10 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

BCL2L10 Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK. Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1. Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney. Belongs to the Bcl-2 family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Apoptosis
Cellular Component: mitochondrial outer membrane; nuclear membrane; membrane; mitochondrion; integral to membrane; cytosol
Molecular Function: protein binding; protein homodimerization activity; protein heterodimerization activity
Biological Process: caspase activation; DNA damage response, signal transduction resulting in induction of apoptosis; positive regulation of apoptosis; female gamete generation; spermatogenesis; negative regulation of apoptosis
Reference #:  Q9HD36 (UniProtKB)
Alt. Names/Synonyms: Anti-apoptotic protein NrH; Apoptosis regulator Bcl-B; B2L10; Bcl-2-like protein 10; BCL-B; Bcl2-L-10; BCL2-like 10 (apoptosis facilitator); BCL2L10; BCLB; Boo; Diva; MGC129810; MGC129811
Gene Symbols: BCL2L10
Molecular weight: 21,973 Da
Basal Isoelectric point: 9.63  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend

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SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.



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