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Protein Page:
BCL2L10 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
BCL2L10 Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK. Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1. Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney. Belongs to the Bcl-2 family. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Membrane protein, integral
Cellular Component: nuclear membrane; mitochondrion; membrane; integral to membrane; cytosol
Molecular Function: protein binding
Biological Process: caspase activation; female gamete generation; spermatogenesis; negative regulation of apoptosis
Reference #:  Q9HD36 (UniProtKB)
Alt. Names/Synonyms: Anti-apoptotic protein NrH; Apoptosis regulator Bcl-B; B2L10; Bcl-2-like protein 10; BCL-B; Bcl2-L-10; BCL2-like 10 (apoptosis facilitator); BCL2L10; BCLB; Boo; Diva; MGC129810; MGC129811
Gene Symbols: BCL2L10
Molecular weight: 21,973 Da
Basal Isoelectric point: 9.63  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

BCL2L10
Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 1 T92-p GRVVTLVtFAGtLLE
0 1 T96-p TLVtFAGtLLERGPL
0 1 K109-u PLVTARWkkWGFQPR
0 1 K110-u LVTARWkkWGFQPRL
  mouse

 
A95 SQLVMLLAFAGTLMN
T99 MLLAFAGTLMNQGPY
K112 PYMAVKQKRDLGNRV
R113 YMAVKQKRDLGNRVI
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