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Protein Page:
CLCA4 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
CLCA4 May be involved in mediating calcium-activated chloride conductance. Belongs to the CLCR family. Note: This description may include information from UniProtKB.
Protein type: Channel, chloride; Membrane protein, integral
Cellular Component: integral to plasma membrane; apical plasma membrane
Molecular Function: chloride channel activity
Biological Process: transport; chloride transport
Reference #:  Q14CN2 (UniProtKB)
Alt. Names/Synonyms: CaCC; CaCC-2; CaCC2; Calcium-activated chloride channel family member 4; Calcium-activated chloride channel protein 2; Calcium-activated chloride channel regulator 4; Calcium-activated chloride channel regulator 4, 110 kDa form; Calcium-activated chloride channel regulator 4, 30 kDa form; chloride channel accessory 4; chloride channel regulator 4; chloride channel, calcium activated, family member 4; CLCA4; hCaCC-2; hCLCA4; MGC142247; MGC142249
Gene Symbols: CLCA4
Molecular weight: 101,283 Da
Basal Isoelectric point: 5.27  Predict pI for various phosphorylation states
Select Structure to View Below

CLCA4

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 Y198 ISGRNRVYKCQGGSC
0 1 S204 VYKCQGGSCLSRACR
0 1 S236-p KVQTEKAsIMFMQSI
0 1 I265 EAPSLQNIKCNFRST
0 1 K266 APSLQNIKCNFRSTW
0 1 S364-p NKLIQIKsSDERNTL
0 1 S589-p VTSRAANsSVPPITV
0 1 S803-p SILDLRDsFDDALQV
  mouse

 
Y199-p ITGTNRVyACQGGsC
S205-p VyACQGGsCAMRRCR
S237 KVQSEKASIMFMQSI
K266-ub EAPTLHNkkCNYRST
K267-ub APTLHNkkCNYRSTW
S365 HELIQINSDIERNQL
S590 VTSRAANSSVPPITV
N804 NIIELRDNFNNSPRV
  rat

 
Q199 IKGMNKAQVCQGGSC
S205 AQVCQGGSCITRNCR
S237 KVQTEKSSIMFMQSI
Q266 EAPTLHNQKCDYRST
K267 APTLHNQKCDYRSTW
S365 SELIQINSDVERNQL
P590 VTSRASRPSVPPIIV
N804 NIIDLRDNFNKSLQV
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