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Protein Page:
CLCA4 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
CLCA4 May be involved in mediating calcium-activated chloride conductance. Belongs to the CLCR family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Channel, chloride
Cellular Component: integral to plasma membrane; apical plasma membrane; extracellular region
Molecular Function: chloride channel activity
Biological Process: transport; chloride transport
Reference #:  Q6UX81 (UniProtKB)
Alt. Names/Synonyms: CaCC; CaCC-2; CaCC2; Calcium-activated chloride channel family member 4; Calcium-activated chloride channel protein 2; Calcium-activated chloride channel regulator 4; Calcium-activated chloride channel regulator 4, 110 kDa form; Calcium-activated chloride channel regulator 4, 30 kDa form; chloride channel accessory 4; chloride channel regulator 4; chloride channel, calcium activated, family member 4; CLCA4; hCaCC-2; hCLCA4; MGC142247; MGC142249
Gene Symbols: CLCA4
Molecular weight: 101,283 Da
Basal Isoelectric point: 5.27  Predict pI for various phosphorylation states
Select Structure to View Below

CLCA4
Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 1 Y168-p RWGVFDEyNEDQPFy
0 1 Y175-p yNEDQPFyRAKSKKI
0 1 Y198 ISGRNRVYKCQGGSC
0 1 S204 VYKCQGGSCLSRACR
0 1 S236-p KVQTEKAsIMFMQSI
0 1 I265 EAPSLQNIkCNFRST
0 1 K266-u APSLQNIkCNFRSTW
0 1 S589-p VTSRAANsSVPPITV
0 1 S803-p SILDLRDsFDDALQV
0 1 S858-p SNLTSKVsNIAQVtL
0 1 T864-p VsNIAQVtLFIPQAN
0 1 T882-p IDPTPTPtPTPTPDK
  mouse

 
Y169 RWGVFDEYNEDQPFY
Y176 YNEDQPFYSASSKKI
Y199-p ITGTNRVyACQGGsC
S205-p VyACQGGsCAMRRCR
S237 KVQSEKASIMFMQSI
K266-u EAPTLHNkkCNYRST
K267-u APTLHNkkCNYRSTW
S590 VTSRAANSSVPPITV
N804 NIIELRDNFNNSPRV
S859 SSLSSGPSNIAQVAL
A865 PSNIAQVALFTPQAE
- gap
  rat

 
Y169 RWGVFDEYNEDQPFY
Y176 YNEDQPFYSASSKKI
Q199 IKGMNKAQVCQGGSC
S205 AQVCQGGSCITRNCR
S237 KVQTEKSSIMFMQSI
Q266 EAPTLHNQKCDYRST
K267 APTLHNQKCDYRSTW
P590 VTSRASRPSVPPIIV
N804 NIIDLRDNFNKSLQV
S859 SNLHSGLSNIAQVAL
A865 LSNIAQVALFTPQAD
- gap
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