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Protein Page:
SESN2 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
SESN2 Involved in the reduction of peroxiredoxins. Widely expressed. Belongs to the sestrin family. Note: This description may include information from UniProtKB.
Protein type: Enzyme, misc.
Cellular Component: cytoplasm; nucleus
Biological Process: cell cycle arrest
Reference #:  P58004 (UniProtKB)
Alt. Names/Synonyms: DKFZp761M0212; DKFZp761M02121; Hi95; hypoxia induced gene 95; SES2; SESN2; SEST2; sestrin 2; Sestrin-2
Gene Symbols: SESN2
Molecular weight: 54,494 Da
Basal Isoelectric point: 5.57  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

SESN2
Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 1 S45-p RRGPRGPsAFIPVEE
0 1 Y323-p VEDPTFGyEDFTRRG
0 1 Y342-p PTFRAQDyTWEDHGY
0 1 Y356-p YSLIQRLyPEGGQLL
0 1 K434-u TVACYPEkTTRRMYN
0 1 Y470-p RMQAALLyALRAITR
  mouse

 
S45 RRGSRGPSAFIPVEE
Y323 VEDPAFGYEDFTRRG
Y342 PTFRAQDYTWEDHGY
Y356 YSLIQRLYPEGGQLL
K434 TVACYPEKTTRRMYN
Y470 RMQAALLYALRAITR
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