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Protein Page:
FAIM (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
FAIM Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Belongs to the FAIM1 family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 3q22.3
Cellular Component: cytoplasm
Biological Process: apoptosis; negative regulation of apoptosis
Reference #:  Q9NVQ4 (UniProtKB)
Alt. Names/Synonyms: FAIM; FAIM1; Fas apoptotic inhibitory molecule; Fas apoptotic inhibitory molecule 1
Gene Symbols: FAIM
Molecular weight: 20,215 Da
Basal Isoelectric point: 5.55  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

FAIM

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 - gap
0 2 - gap
0 1 - gap
0 1 K47-ub IRKEWMFkLVGKETF
0 1 K160-ub AVSSGKRkEGIIHTL
0 1 S179-p REIPEIAs_______
  mouse

► Hide Isoforms
 
- gap
- gap
- gap
K47 IRREWMFKLVGKETF
K160 AVSSGKRKEGIIHTL
T178 NREIPELTQ______
  FAIM iso3  
S3-p _____MAsGDDsPIF
S7-p _MAsGDDsPIFEDDE
S15-p PIFEDDEsPLYSLEK
K69 IRREWMFKLVGKETF
K182 AVSSGKRKEGIIHTL
T200 NREIPELTQ______
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