Involved in the activation cascade of caspases responsible for apoptosis execution (By similarity). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Loss of zygotic DCP-1 function causes larval lethality and melanotic tumors.
Protein type: Endoplasmic reticulum; EC 220.127.116.11; Protease; Mitochondrial; Apoptosis
Molecular Function: protein binding; cysteine-type endopeptidase activity
Biological Process: oogenesis; apoptosis; multicellular organismal development; salivary gland cell autophagic cell death; programmed cell death; actin filament organization; ovarian nurse cell to oocyte transport; nurse cell apoptosis; cellular response to starvation; proteolysis; cytoplasmic transport, nurse cell to oocyte; embryonic development; autophagic cell death; actin cytoskeleton organization and biogenesis; positive regulation of macroautophagy; positive regulation of autophagy; neuron remodeling
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.