delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1p36.1-p34.3
Cellular Component: postsynaptic membrane; integral to plasma membrane; cytoplasm; plasma membrane; nerve terminal; vesicle; intrinsic to plasma membrane; lipid raft
Molecular Function: protein binding; opioid receptor activity
Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor protein signaling pathway; protein import into nucleus, translocation; adult locomotory behavior; neuropeptide signaling pathway; immune response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); regulation of sensory perception of pain; regulation of calcium ion transport; G-protein signaling, adenylate cyclase inhibiting pathway
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.