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Protein Page:
RPL17 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
RPL17 a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene. [provided by RefSeq, Dec 2010]
Protein type: Translation; Ribosomal protein
Chromosomal Location of Human Ortholog: 18q21
Cellular Component: nucleus; cytosol
Molecular Function: structural constituent of ribosome
Biological Process: SRP-dependent cotranslational protein targeting to membrane; translation; viral reproduction; translational termination; viral infectious cycle; mRNA metabolic process; translational elongation; cellular protein metabolic process; RNA metabolic process; translational initiation; mRNA catabolic process, nonsense-mediated decay; gene expression; viral transcription
Reference #:  P18621 (UniProtKB)
Alt. Names/Synonyms: 60S ribosomal protein L17; 60S ribosomal protein L23; FLJ92089; gene encoding putative NFkB activating protein; MGC117162; PD-1; ribosomal protein L17; RL17; RPL17; rpL23
Gene Symbols: RPL17
Molecular weight: 21,397 Da
Basal Isoelectric point: 10.18  Predict pI for various phosphorylation states
Select Structure to View Below

RPL17

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 Y4 ____MVRYsLDPENP
0 6 S5-p ___MVRYsLDPENPT
0 7 K13-ub LDPENPTksCKSRGS
0 1 S14-p DPENPTksCKSRGSN
0 1 K16 ENPTksCKSRGSNLR
0 1 K37-ac RETAQAIkGMHIRKA
0 1 K37 RETAQAIKGMHIRKA
0 1 K49-ac RKATKYLkDVTLQkQ
0 3 K49-ub RKATKYLkDVTLQkQ
0 6 K55-ub LkDVTLQkQCVPFRR
0 3 K74-ac VGRCAQAkQWGWTQG
0 14 K74-ub VGRCAQAkQWGWTQG
0 1 K85-ac WTQGRWPkksAEFLL
0 2 K86-ub TQGRWPkksAEFLLH
0 1 S87-p QGRWPkksAEFLLHM
0 37 K96-ub EFLLHMLkNAESNAE
0 1 K96-sc EFLLHMLkNAESNAE
0 3 K105-ub AESNAELkGLDVdSL
0 1 D110-ca ELkGLDVdSLVIEHI
0 2 T129-p APKMRRRtYRAHGRI
0 1 R131 KMRRRtYRAHGRINP
0 2 Y139-p AHGRINPyMssPCHI
0 5 S141-p GRINPyMssPCHIEM
0 22 S142-p RINPyMssPCHIEMI
0 1 K159 EKEQIVPKPEEEVAQ
0 1 K167-sc PEEEVAQkKKIsQKK
0 7 S171-p VAQkKKIsQKKLKKQ
  mouse

 
Y4-p ____MVRySLDPENP
S5 ___MVRySLDPENPT
K13-ub LDPENPTkSCkSRGS
S14 DPENPTkSCkSRGSN
K16-ub ENPTkSCkSRGSNLR
K37 RETAQAIKGMHIRKA
K37-ub RETAQAIkGMHIRKA
K49-ac RKATKYLkDVTLKkQ
K49-ub RKATKYLkDVTLKkQ
K55-ub LkDVTLKkQCVPFRR
K74 VGRCAQAKQWGWTQG
K74-ub VGRCAQAkQWGWTQG
K85 WTQGRWPKKSAEFLL
K86 TQGRWPKKSAEFLLH
S87 QGRWPKKSAEFLLHM
K96-ub EFLLHMLkNAESNAE
K96 EFLLHMLKNAESNAE
K105-ub AESNAELkGLDVDSL
D110 ELkGLDVDSLVIEHI
T129 APKMRRRTYrAHGRI
R131-m2 KMRRRTYrAHGRINP
Y139-p AHGRINPyMssPCHI
S141-p GRINPyMssPCHIEM
S142-p RINPyMssPCHIEMI
K159-ac EKEQIVPkPEEEVAQ
K167 PEEEVAQKKKISQKK
S171 VAQKKKISQKKLKKQ
  rat

 
Y4 ____MVRYSLDPENP
S5 ___MVRYSLDPENPT
K13 LDPENPTKSCKSRGS
S14 DPENPTKSCKSRGSN
K16 ENPTKSCKSRGSNLR
K37-ac RETAQAIkGMHIRKA
K37 RETAQAIKGMHIRKA
K49-ac RKATKYLkDVTLKKQ
K49 RKATKYLKDVTLKKQ
K55 LkDVTLKKQCVPLRR
K74 VDRCAQAKQWGWTQG
K74 VDRCAQAKQWGWTQG
K85 WTQGRWPKKSAEFLL
K86 TQGRWPKKSAEFLLH
S87 QGRWPKKSAEFLLHM
K96 EFLLHMLKNAESNAE
K96 EFLLHMLKNAESNAE
K105 AESNAELKGLDVDSL
D110 ELKGLDVDSLVIEHI
T129 APKMRRRTYRAHSRI
R131 KMRRRTYRAHSRINP
Y139 AHSRINPYMSSPCHI
S141 SRINPYMSSPCHIEM
S142 RINPYMSSPCHIEMI
K159-ac EKEQIVPkPEEEVAQ
K167 PEEEVAQKKKISQKK
S171 VAQKKKISQKKLKRQ
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