Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes. Belongs to the synaptobrevin family. Note: This description may include information from UniProtKB.
Protein type: Vesicle protein; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p12-p11.2
Cellular Component: SNARE complex; recycling endosome; mitochondrion; membrane; lysosomal membrane; late endosome membrane; secretory granule membrane; early endosome; integral to membrane; plasma membrane
Molecular Function: syntaxin binding
Biological Process: vesicle fusion; protein transport; entry of virus into host cell; autophagic vacuole fusion; regulation of endocytosis; protein complex assembly; post-Golgi vesicle-mediated transport
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.