Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. Interacts with SRPX2. Belongs to the peptidase C1 family. Note: This description may include information from UniProtKB.
Protein type: Autophagy; Protease; Motility/polarity/chemotaxis; EC 188.8.131.52
Cellular Component: extracellular space; intracellular membrane-bound organelle; mitochondrion; lysosome; perinuclear region of cytoplasm; extracellular region; melanosome; nucleolus; intracellular
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.