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FABP7 (human)

Overview FABP7 B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Note: This description may include information from UniProtKB. Protein type: Cell cycle regulation; Cell development/differentiation; Lipid binding protein Cellular Component: cell projection; cell soma; cytoplasm; nucleus Molecular Function: transporter activity; lipid binding Biological Process: negative regulation of cell proliferation; nervous system development; epithelial cell proliferation; prepulse inhibition; neurogenesis; cell proliferation in forebrain Reference #:  O15540 (UniProtKB) Alt. Names/Synonyms: B-FABP; BLBP; brain lipid binding protein; Brain lipid-binding protein; Brain-type fatty acid-binding protein; DKFZp547J2313; FABP7; FABPB; fatty acid binding protein 7, brain; Fatty acid-binding protein 7; Fatty acid-binding protein, brain; Mammary-derived growth inhibitor related; mammary-derived growth inhibitor-related; MRG Gene Symbols: FABP7 Molecular weight: 14,889 Da Basal Isoelectric point: 5.4  Predict pI for various phosphorylation states

Select Structure to View Below FABP7 1FDQ - A/B=1-132 (human) 1FE3 - A=1-132 (human) 1JJX - A=1-132 (human)

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB 1FDQ 1FE3 1JJX  |  Phospho3D  |  DISEASE  |  UCSD-Nature  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		K22	QNFDEYMKALGVGFA
0	1		T54-p	GDKVVIRtLStFKNt
0	1		T57-p	VVIRtLStFKNtEIS
0	1		T61-p	tLStFKNtEISFQLG
0	1		T117-p	KDGKMVMtLtFGDVV
0	1		T119-p	GKMVMtLtFGDVVAV
0	1		Y129-p	DVVAVRHyEKA____

	mouse
K22-u	QNFDEYMkALGVGFA
T54	GGKVVIRTQCTFKNT
T57	VVIRTQCTFKNTEIN
T61	TQCTFKNTEINFQLG
T117	KDGKMVVTLTFGDIV
T119	GKMVVTLTFGDIVAV
Y129	DIVAVRCYEKA____

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