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Protein Page:
TNFSF15 (human)

Overview
TNFSF15 Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. Belongs to the tumor necrosis factor family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Apoptosis; Membrane protein, integral
Cellular Component: extracellular space; integral to plasma membrane; plasma membrane; integral to membrane
Molecular Function: death receptor binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding
Biological Process: caspase activation; cytokine metabolic process; activation of NF-kappaB-inducing kinase; immune response; signal transduction; positive regulation of cytokine secretion
Reference #:  O95150 (UniProtKB)
Alt. Names/Synonyms: TL1; TL1A; tumor necrosis factor (ligand) superfamily, member 15; VEGI; VEGI192A
Gene Symbols: TNFSF15
Molecular weight: 28,087 Da
Basal Isoelectric point: 6.31  Predict pI for various phosphorylation states
Select Structure to View Below

TNFSF15

Protein Structure Not Found.


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