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Protein Page:
IL5 (human)

IL5 Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. Belongs to the IL-5 family. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 5q31.1
Cellular Component: extracellular space; extracellular region; intracellular
Molecular Function: protein binding; interleukin-5 receptor binding; growth factor activity; cytokine activity
Biological Process: epidermal growth factor receptor signaling pathway; axon guidance; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; activation of MAPKK activity; cytokine and chemokine mediated signaling pathway; MAPKKK cascade; positive regulation of JAK-STAT cascade; positive regulation of immunoglobulin secretion; positive regulation of peptidyl-tyrosine phosphorylation; small GTPase mediated signal transduction; Ras protein signal transduction; positive regulation of B cell proliferation; insulin receptor signaling pathway; innate immune response; positive regulation of transcription factor activity; inflammatory response; vascular endothelial growth factor receptor signaling pathway; positive regulation of eosinophil differentiation
Reference #:  P05113 (UniProtKB)
Alt. Names/Synonyms: EDF; IL-5; interleukin 5 (colony-stimulating factor, eosinophil); TRF
Gene Symbols: IL5
Molecular weight: 15,238 Da
Basal Isoelectric point: 7.81  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  

Show Multiple Sequence Alignment


LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.



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